The Relationship Between Dopamine Neurotransmitter Dynamics and the Blood-Oxygen-Level-Dependent (BOLD) Signal: A Review of Pharmacological Functional Magnetic Resonance Imaging
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bruinsma, Tyler J. | - |
dc.contributor.author | Sarma, Vidur V. | - |
dc.contributor.author | Oh, Yoonbae | - |
dc.contributor.author | Jang, Dong Pyo | - |
dc.contributor.author | Chang, Su-Youne | - |
dc.contributor.author | Worrell, Greg A. | - |
dc.contributor.author | Lowe, Val J. | - |
dc.contributor.author | Jo, Hang Joon | - |
dc.contributor.author | Min, Hoon-Ki | - |
dc.date.accessioned | 2022-07-12T02:29:59Z | - |
dc.date.available | 2022-07-12T02:29:59Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-04 | - |
dc.identifier.issn | 1662-4548 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150291 | - |
dc.description.abstract | Functional magnetic resonance imaging (fMRI) is widely used in investigations of normal cognition and brain disease and in various clinical applications. Pharmacological fMRI (pharma-fMRI) is a relatively new application, which is being used to elucidate the effects and mechanisms of pharmacological modulation of brain activity. Characterizing the effects of neuropharmacological agents on regional brain activity using fMRI is challenging because drugs modulate neuronal function in a wide variety of ways, including through receptor agonist, antagonist, and neurotransmitter reuptake blocker events. Here we review current knowledge on neurotransmitter-mediated blood-oxygen-level dependent (BOLD) fMRI mechanisms as well as recently updated methodologies aimed at more fully describing the effects of neuropharmacologic agents on the BOLD signal. We limit our discussion to dopaminergic signaling as a useful lens through which to analyze and interpret neurochemical-mediated changes in the hemodynamic BOLD response. We also discuss the need for future studies that use multi-modal approaches to expand the understanding and application of pharma-fMRI. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.title | The Relationship Between Dopamine Neurotransmitter Dynamics and the Blood-Oxygen-Level-Dependent (BOLD) Signal: A Review of Pharmacological Functional Magnetic Resonance Imaging | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jang, Dong Pyo | - |
dc.contributor.affiliatedAuthor | Jo, Hang Joon | - |
dc.identifier.doi | 10.3389/fnins.2018.00238 | - |
dc.identifier.scopusid | 2-s2.0-85045250254 | - |
dc.identifier.wosid | 000429597500001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN NEUROSCIENCE, v.12, pp.1 - 8 | - |
dc.relation.isPartOf | FRONTIERS IN NEUROSCIENCE | - |
dc.citation.title | FRONTIERS IN NEUROSCIENCE | - |
dc.citation.volume | 12 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 8 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | DEEP BRAIN-STIMULATION | - |
dc.subject.keywordPlus | REWARD-SEEKING BEHAVIOR | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | NUCLEUS-ACCUMBENS | - |
dc.subject.keywordPlus | NEURONAL-ACTIVITY | - |
dc.subject.keywordPlus | COCAINE-SEEKING | - |
dc.subject.keywordPlus | BASAL GANGLIA | - |
dc.subject.keywordPlus | FMRI SIGNAL | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordAuthor | dopamine | - |
dc.subject.keywordAuthor | BOLD | - |
dc.subject.keywordAuthor | fMRI | - |
dc.subject.keywordAuthor | pharma-fMRI | - |
dc.subject.keywordAuthor | fast-scan cyclic voltammetry | - |
dc.identifier.url | https://www.frontiersin.org/articles/10.3389/fnins.2018.00238/full | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.