Prognostic Implications of Postoperative Infectious Complications in Non-Small Cell Lung Cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jang, Hyo Joon | - |
dc.contributor.author | Song, Jae Won | - |
dc.contributor.author | Cho, Sukki | - |
dc.contributor.author | Kim, Kwhanmien | - |
dc.contributor.author | Jheon, Sanghoon | - |
dc.date.accessioned | 2022-07-12T12:55:44Z | - |
dc.date.available | 2022-07-12T12:55:44Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 2233-601X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150575 | - |
dc.description.abstract | Background: Few studies have evaluated the long-term impact of postoperative infectious complications in patients with non-small cell lung cancer (NSCLC). We aimed to determine the impact of infectious complications on long-term outcomes after surgical resection for NSCLC. Methods: We performed a retrospective study of 1,380 eligible patients who underwent pulmonary resection for NSCLC from 2003 to 2012. Complications were divided into infectious complications and non-infectious complications. Kaplan-Meier survival analysis was used to compare unadjusted 5-year cancer-specific survival (CSS) rates and recurrence-free survival (RFS) rates. Cox regression was used to determine the impact of infectious complications on 5-year CSS and RFS. Results: The rate of total complications and infectious complications was 24.3% and 4.3%, respectively. In the node-negative subgroup, the 5-year CSS and RFS rates were 75.9% and 57.1% in patients who had infectious complications, compared to 87.9% and 78.4% in patients who had no complications. Infectious complications were a negative prognostic factor for 5-year RFS (hazard ratio, 1.92; 95% confidence interval, 1.00–3.69; p=0.049). In the node-positive subgroup, the 5-year CSS rate and RFS were 44.6% and 48.4% in patients who had infectious complications, compared to 70.5% and 48.4% for patients who had no complications. Conclusion: Postoperative infectious complications had a negative impact on CSS and RFS in node-negative NSCLC. Our findings may help improve risk assessment for tumor recurrence after pulmonary resection for node-negative NSCLC. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한흉부외과학회 | - |
dc.title | Prognostic Implications of Postoperative Infectious Complications in Non-Small Cell Lung Cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jang, Hyo Joon | - |
dc.identifier.doi | 10.5090/kjtcs.2018.51.1.41 | - |
dc.identifier.scopusid | 2-s2.0-85041321967 | - |
dc.identifier.bibliographicCitation | Korean Journal of Thoracic and Cardiovascular Surgery, v.51, no.1, pp.41 - 52 | - |
dc.relation.isPartOf | Korean Journal of Thoracic and Cardiovascular Surgery | - |
dc.citation.title | Korean Journal of Thoracic and Cardiovascular Surgery | - |
dc.citation.volume | 51 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 41 | - |
dc.citation.endPage | 52 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002313984 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Non-small-cell lung carcinoma | - |
dc.subject.keywordAuthor | Complication | - |
dc.subject.keywordAuthor | Prognosis | - |
dc.identifier.url | https://pdfs.semanticscholar.org/87e2/9c2f9327fd28f0544eb45e4718217a30eb26.pdf | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.