Effects of nefopam with fentanyl in intravenous patient-controlled analgesia after arthroscopic orthopedic surgery: a prospective double-blind randomized trial
DC Field | Value | Language |
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dc.contributor.author | Oh, You Na | - |
dc.contributor.author | Kim, Kyu Nam | - |
dc.contributor.author | Jeong, Mi Ae | - |
dc.contributor.author | Kim, Dong Won | - |
dc.contributor.author | Kim, Ji Yoon | - |
dc.contributor.author | Ki, Hyun Seo | - |
dc.date.accessioned | 2022-07-12T19:59:27Z | - |
dc.date.available | 2022-07-12T19:59:27Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1300-0144 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150866 | - |
dc.description.abstract | Background/aim: We performed this prospective randomized double-blind study to compare the effects of nefopam versus ketorolac in intravenous fentanyl-based patient-controlled analgesia (PCA) after shoulder arthroscopic orthopedic surgery. Materials and methods: Ninety-two patients were randomly divided into two groups to receive intravenous PCA. Patients were assigned to either the nefopam group (nefopam 120 mg and fentanyl 20 mu g/kg) or the ketorolac group (ketorolac 2 mg/kg and fentanyl 20 mu g/kg). Pain was assessed on a visual analogue scale (VAS) and a numeric rating scale (NRS). Additionally, patient satisfaction, adverse events, and vital signs were monitored. Results: There were no significant differences in VAS score (P = 0.48) or NRS score (P = 0.15) between the two groups. Similarly, patient satisfaction did not differ between the two groups [8.5(0.8) vs. 8.2(1.0), P = 0.14]. There were no statistically significant differences in the incidence of nausea (P = 0.72), vomiting (P = 0.46), urinary retention (P = 0.82), sweating (P = 0.49), or dizziness (P = 0.45) between the two groups. Likewise, there were no differences in heart rate [78.2(7.7) vs. 75.2(6.5), P = 0.18] or SpO2 [98.4(1.8) vs. 98.5(1.9), P = 0.83]. Conclusion: Nefopam is an appropriate alternative for co-administration with fentanyl-based PCA in patients who have difficulty using nonsteroidal antiinflammatory drugs. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY | - |
dc.title | Effects of nefopam with fentanyl in intravenous patient-controlled analgesia after arthroscopic orthopedic surgery: a prospective double-blind randomized trial | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Kyu Nam | - |
dc.contributor.affiliatedAuthor | Jeong, Mi Ae | - |
dc.contributor.affiliatedAuthor | Kim, Dong Won | - |
dc.identifier.doi | 10.3906/sag-1707-113 | - |
dc.identifier.scopusid | 2-s2.0-85042470673 | - |
dc.identifier.wosid | 000425902900024 | - |
dc.identifier.bibliographicCitation | TURKISH JOURNAL OF MEDICAL SCIENCES, v.48, no.1, pp.142 - 149 | - |
dc.relation.isPartOf | TURKISH JOURNAL OF MEDICAL SCIENCES | - |
dc.citation.title | TURKISH JOURNAL OF MEDICAL SCIENCES | - |
dc.citation.volume | 48 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 142 | - |
dc.citation.endPage | 149 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | - |
dc.subject.keywordPlus | POSTOPERATIVE PAIN | - |
dc.subject.keywordPlus | MULTIMODAL ANALGESIA | - |
dc.subject.keywordPlus | PLATELET-FUNCTION | - |
dc.subject.keywordPlus | MORPHINE | - |
dc.subject.keywordPlus | KETOROLAC | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordPlus | ULCER | - |
dc.subject.keywordAuthor | Analgesia | - |
dc.subject.keywordAuthor | balanced | - |
dc.subject.keywordAuthor | analgesia | - |
dc.subject.keywordAuthor | patient-controlled | - |
dc.subject.keywordAuthor | nefopam | - |
dc.subject.keywordAuthor | randomized controlled trial | - |
dc.identifier.url | https://journals.tubitak.gov.tr/medical/issues/sag-18-48-1/sag-48-1-24-1707-113.pdf | - |
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