Zika virus directly infects peripheral neurons and induces cell death
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Yohan | - |
dc.contributor.author | Zhang, Feiran | - |
dc.contributor.author | Wang, Yaqing | - |
dc.contributor.author | Lee, Emily M. | - |
dc.contributor.author | Choi, In Young | - |
dc.contributor.author | Lim, Hotae | - |
dc.contributor.author | Mirakhori, Fahimeh | - |
dc.contributor.author | Li, Ronghua | - |
dc.contributor.author | Huang, Luoxiu | - |
dc.contributor.author | Xu, Tianlei | - |
dc.contributor.author | Wu, Hao | - |
dc.contributor.author | Li, Cui | - |
dc.contributor.author | Qin, Cheng-Feng | - |
dc.contributor.author | Wen, Zhexing | - |
dc.contributor.author | Wu, Qing-Feng | - |
dc.contributor.author | Tang, Hengli | - |
dc.contributor.author | Xu, Zhiheng | - |
dc.contributor.author | Jin, Peng | - |
dc.contributor.author | Song, Hongjun | - |
dc.contributor.author | Ming, Guo-li | - |
dc.contributor.author | Lee, Gabsang | - |
dc.date.accessioned | 2022-07-13T11:29:46Z | - |
dc.date.available | 2022-07-13T11:29:46Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 1097-6256 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151596 | - |
dc.description.abstract | Zika virus (ZIKV) infection is associated with neurological disorders of both the CNS and peripheral nervous systems (PNS), yet few studies have directly examined PNS infection. Here we show that intraperitoneally or intraventricularly injected ZIKV in the mouse can infect and impact peripheral neurons in vivo. Moreover, ZIKV productively infects stemcell- derived human neural crest cells and peripheral neurons in vitro, leading to increased cell death, transcriptional dysregulation and cell-type-specific molecular pathology. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE RESEARCH | - |
dc.title | Zika virus directly infects peripheral neurons and induces cell death | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Yohan | - |
dc.identifier.doi | 10.1038/nn.4612 | - |
dc.identifier.scopusid | 2-s2.0-85028463914 | - |
dc.identifier.wosid | 000408587700006 | - |
dc.identifier.bibliographicCitation | NATURE NEUROSCIENCE, v.20, no.9, pp.1209 - 1212 | - |
dc.relation.isPartOf | NATURE NEUROSCIENCE | - |
dc.citation.title | NATURE NEUROSCIENCE | - |
dc.citation.volume | 20 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1209 | - |
dc.citation.endPage | 1212 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | EMBRYONIC STEM-CELLS | - |
dc.subject.keywordPlus | NEURAL CREST CELLS | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | PROGENITORS | - |
dc.subject.keywordPlus | DERIVATION | - |
dc.subject.keywordPlus | EXPOSURE | - |
dc.subject.keywordPlus | MODELS | - |
dc.subject.keywordPlus | BRAIN | - |
dc.identifier.url | https://www.nature.com/articles/nn.4612 | - |
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