Pan-genome analysis of Bacillus for microbiome profiling
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yihwan | - |
dc.contributor.author | Koh, InSong | - |
dc.contributor.author | Lim, Mi Young | - |
dc.contributor.author | Chung, Won-Hyong | - |
dc.contributor.author | Rho, Mina | - |
dc.date.accessioned | 2022-07-13T12:05:13Z | - |
dc.date.available | 2022-07-13T12:05:13Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151737 | - |
dc.description.abstract | Recent advances in high-throughput sequencing technology allow for in-depth studies on microbial genomes and their communities. While multiple strains of the same species could display genomic variations with different gene contents in diverse habitats and hosts, the essential functions for a specific species are conserved as core genes that are shared among strains. We have comprehensively analyzed 238 strains of five different Bacillus species to identify the properties of core and strain-specific genes. Core and strain-specific genes in each Bacillus species show significant differences in their functions and genomic signatures. Using the core genes defined in this study, we have precisely identified the Bacillus species that exist in food microbiomes. Without resorting to culture-based whole genome sequencing, an unexpectedly large portion of the core genes, 98.22% of core genes in B. amyloliquefaciens and 97.77% of B. subtilis, were reconstructed from the microbiome. We have performed a pan-genome analysis on the core gene data of multiple Bacillus species to investigate the Bacillus species in food microbiome. Our findings provide a comprehensive genetic landscape of the Bacillus species, which is also consistent with previous studies on a limited number of strains and species. Analysis based on comprehensive core genes should thus serve as a powerful profiling tool to better understand major constituents in fermented food microbiomes. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.title | Pan-genome analysis of Bacillus for microbiome profiling | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, InSong | - |
dc.contributor.affiliatedAuthor | Rho, Mina | - |
dc.identifier.doi | 10.1038/s41598-017-11385-9 | - |
dc.identifier.scopusid | 2-s2.0-85028975787 | - |
dc.identifier.wosid | 000409841100046 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.7 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | MULTIPLE SEQUENCE ALIGNMENT | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | EVOLUTION | - |
dc.subject.keywordPlus | ANTHRACIS | - |
dc.subject.keywordPlus | STRAINS | - |
dc.subject.keywordPlus | GENES | - |
dc.subject.keywordPlus | SCALE | - |
dc.identifier.url | https://www.nature.com/articles/s41598-017-11385-9 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.