Levofloxacin 유발 고정약진 1예Levofloxacin-induced fixed drug eruption: A case report
- Other Titles
- Levofloxacin-induced fixed drug eruption: A case report
- Authors
- Han, Sung Soo; Oh, Eui Hyun; Kwon, Hyoung Il; Ko, Joo Yeon; Ro, Young Suck; Kim, Jeong Eun
- Issue Date
- Aug-2017
- Publisher
- Korean Dermatological Association
- Keywords
- Fixed drug eruption; Levofloxacin
- Citation
- Korean Journal of Dermatology, v.55, no.7, pp.445 - 448
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Journal of Dermatology
- Volume
- 55
- Number
- 7
- Start Page
- 445
- End Page
- 448
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151848
- ISSN
- 0494-4739
- Abstract
- Fixed drug eruptions (FDEs) are characterized by the presence of site-specific recurrence of a solitary or multiple, well-circumscribed, erythematous macules or patches that recur with each exposure to a particular medication. Several drugs including non-steroidal anti-inflammatory drugs, non-opioid analgesics, sedatives, anticonvulsants, sulfonamides, and tetracycline have been associated with an increased risk of inducing FDE. A 45-year-old woman with known history of levofloxacin use presented with erythematous patches on her face and left forearm. Although a patch test to levofloxacin showed a negative reaction, intradermal tests to assess hypersensitivity to levofloxacin were positive, and she was diagnosed with levofloxacin-induced FDE. Her antibiotic was switched to moxifloxacin, which she tolerated well. Moxifloxacin did not show cross-reactivity. Because of the widespread use of fluoroquinolones, it is important to consider these as possible etiological agents in cases of FDE. We describe a case of FDE diagnosed using positive intradermal tests to detect sensitivity to levofloxacin.
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