Correlations between Tumor to Background Ratio on Breast-Specific Gamma Imaging and Prognostic Factors in Breast Cancer
DC Field | Value | Language |
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dc.contributor.author | Lee, Soo Jin | - |
dc.contributor.author | Choi, Yun Young | - |
dc.contributor.author | Kim, Chanwoo | - |
dc.contributor.author | Chung, Min Sung | - |
dc.date.accessioned | 2022-07-14T01:57:53Z | - |
dc.date.available | 2022-07-14T01:57:53Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/152235 | - |
dc.description.abstract | The purpose of this study was to investigate the correlations between tumor-to-background ratio (TBR) obtained from breast-specific gamma imaging (BSGI) and the prognostic factors of breast cancer. Sixty-seven patients with invasive ductal carcinoma who underwent preoperative BSGI were enrolled. The BSGI images were visually scored from 1 to 5 according to a breast imaging reporting and data system (BIRADS). The TBR results obtained from positive BSGI images were compared according to the following prognostic factors: tumor size; axillary lymph node metastasis; nuclear grade (NG); histologic grade (HG); subtype; Ki-67; and the expression profile of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Among 67 images, 60 were classified as a positive finding (sensitivity 89.6%). A higher TBR value was significantly correlated with tumor size ≥ 2 cm (P = 0.001), axillary lymph node metastasis (P = 0.007), high HG (P = 0.029), negative PR status (P = 0.036), and Ki-67 ≥ 14% (P = 0.007). The TBR showed a significant difference between the luminal A and non-luminal A subtypes (P = 0.007). On multivariate analysis, TBR had a high correlation with tumor size ≥ 2 cm, axillary lymph node metastasis, and negative PR status (P = 0.003, 0.048, and 0.030, respectively). A high TBR on BSGI was significantly correlated with poor prognostic factors of breast cancer. Luminal A subtype, a breast cancer subtype with more favorable prognosis, was associated with a low TBR on BSGI. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | Correlations between Tumor to Background Ratio on Breast-Specific Gamma Imaging and Prognostic Factors in Breast Cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Yun Young | - |
dc.contributor.affiliatedAuthor | Chung, Min Sung | - |
dc.identifier.doi | 10.3346/jkms.2017.32.6.1031 | - |
dc.identifier.scopusid | 2-s2.0-85018378556 | - |
dc.identifier.wosid | 000403162400021 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.32, no.6, pp.1031 - 1037 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 32 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1031 | - |
dc.citation.endPage | 1037 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002227533 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | TC-99M SESTAMIBI | - |
dc.subject.keywordPlus | ADJUNCT MODALITY | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | TC-99M-SESTAMIBI | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordAuthor | Breast Cancer | - |
dc.subject.keywordAuthor | Gamma Camera Imaging | - |
dc.subject.keywordAuthor | Tc-99m-sestaMIBI | - |
dc.identifier.url | https://jkms.org/DOIx.php?id=10.3346/jkms.2017.32.6.1031 | - |
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