Analysis of Nociceptive Information Encoded in the Temporal Discharge Patterns of Cutaneous C-Fibers
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Kyeongwon | - |
dc.contributor.author | Jang, Jun Ho | - |
dc.contributor.author | Kim, Sung-Phil | - |
dc.contributor.author | Lee, Sang Hoon | - |
dc.contributor.author | Chung, Soon-Cheol | - |
dc.contributor.author | Kim, In Young | - |
dc.contributor.author | Jang, Dong Pyo | - |
dc.contributor.author | Jung, Sung Jun | - |
dc.date.accessioned | 2022-07-15T05:08:45Z | - |
dc.date.available | 2022-07-15T05:08:45Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2016-11 | - |
dc.identifier.issn | 1662-5188 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/153656 | - |
dc.description.abstract | The generation of pain signals from primary afferent neurons is explained by a labeled-line code. However, this notion cannot apply in a simple way to cutaneous C-fibers, which carry signals from a variety of receptors that respond to various stimuli including agonist chemicals. To represent the discharge patterns of C-fibers according to different agonist chemicals, we have developed a quantitative approach using three consecutive spikes. By using this method, the generation of pain in response to chemical stimuli is shown to be dependent on the temporal aspect of the spike trains. Furthermore, under pathological conditions, gamma-aminobutyric acid resulted in pain behavior without change of spike number but with an altered discharge pattern. Our results suggest that information about the agonist chemicals may be encoded in specific temporal patterns of signals in C-fibers, and nociceptive sensation may be influenced by the extent of temporal summation originating from the temporal patterns. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.title | Analysis of Nociceptive Information Encoded in the Temporal Discharge Patterns of Cutaneous C-Fibers | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, In Young | - |
dc.contributor.affiliatedAuthor | Jang, Dong Pyo | - |
dc.contributor.affiliatedAuthor | Jung, Sung Jun | - |
dc.identifier.doi | 10.3389/fncom.2016.00118 | - |
dc.identifier.scopusid | 2-s2.0-84998538578 | - |
dc.identifier.wosid | 000388222900001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN COMPUTATIONAL NEUROSCIENCE, v.10, pp.1 - 12 | - |
dc.relation.isPartOf | FRONTIERS IN COMPUTATIONAL NEUROSCIENCE | - |
dc.citation.title | FRONTIERS IN COMPUTATIONAL NEUROSCIENCE | - |
dc.citation.volume | 10 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 12 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Mathematical & Computational Biology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Mathematical & Computational Biology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | DORSAL-ROOT-GANGLIA | - |
dc.subject.keywordPlus | NEUROPATHIC PAIN | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordPlus | NERVE | - |
dc.subject.keywordPlus | GABA | - |
dc.subject.keywordPlus | DEPOLARIZATION | - |
dc.subject.keywordPlus | FREQUENCY | - |
dc.subject.keywordPlus | STIMULI | - |
dc.subject.keywordPlus | NEURONS | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordAuthor | temporal decoding | - |
dc.subject.keywordAuthor | temporal encoding | - |
dc.subject.keywordAuthor | spike train analysis | - |
dc.subject.keywordAuthor | discharge pattern | - |
dc.subject.keywordAuthor | nociception | - |
dc.identifier.url | https://www.frontiersin.org/articles/10.3389/fncom.2016.00118/full | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.