Analysis of Gastric Microbiota by Pyrosequencing: Minor Role of Bacteria Other Than Helicobacter pylori in the Gastric Carcinogenesis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jo, Hyun Jin | - |
dc.contributor.author | Kim, Jaeyeon | - |
dc.contributor.author | Kim, Nayoung | - |
dc.contributor.author | Park, Ji Hyun | - |
dc.contributor.author | Nam, Ryoung Hee | - |
dc.contributor.author | Seok, Yeong-Jae | - |
dc.contributor.author | Kim, Yeon-Ran | - |
dc.contributor.author | Kim, Joo Sung | - |
dc.contributor.author | Kim, Jung Mogg | - |
dc.contributor.author | Kim, Jung Min | - |
dc.contributor.author | Lee, Dong Ho | - |
dc.contributor.author | Jung, Hyun Chae | - |
dc.date.accessioned | 2022-07-15T05:35:51Z | - |
dc.date.available | 2022-07-15T05:35:51Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 1083-4389 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/153847 | - |
dc.description.abstract | BackgroundLittle is known about the role of gastric microbiota except for Helicobacter pylori (HP) in human health and disease. We compared the differences of human gastric microbiota according to gastric cancer or control and HP infection status and assessed the role of bacteria other than HP. MethodsGastric microbiota of 63 antral mucosal and 18 corpus mucosal samples were analyzed by bar-coded 454 pyrosequencing of the 16S rRNA gene. Antral samples were divided into four subgroups based on HP positivity in pyrosequencing and the presence of cancer. The analysis was focused on bacteria other than HP, especially nitrosating or nitrate-reducing bacteria (NB). The changes of NB in antral mucosa of 16 subjects were followed up. ResultsThe number of NB other than HP (non-HP-NB) was two times higher in the cancer groups than in the control groups, but it did not reach statistical significance. The number of non-HP-NB tends to increase over time, but this phenomenon was prevented by HP eradication in the HP-positive control group, but not in the HP-positive cancer group. ConclusionWe could not find the significant role of bacteria other than HP in the gastric carcinogenesis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Analysis of Gastric Microbiota by Pyrosequencing: Minor Role of Bacteria Other Than Helicobacter pylori in the Gastric Carcinogenesis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jung Mogg | - |
dc.identifier.doi | 10.1111/hel.12293 | - |
dc.identifier.scopusid | 2-s2.0-84986910793 | - |
dc.identifier.wosid | 000384428100003 | - |
dc.identifier.bibliographicCitation | HELICOBACTER, v.21, no.5, pp.364 - 374 | - |
dc.relation.isPartOf | HELICOBACTER | - |
dc.citation.title | HELICOBACTER | - |
dc.citation.volume | 21 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 364 | - |
dc.citation.endPage | 374 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.subject.keywordPlus | GASTROINTESTINAL-TRACT | - |
dc.subject.keywordPlus | ATROPHIC GASTRITIS | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | COLONIZATION | - |
dc.subject.keywordPlus | HISTOLOGY | - |
dc.subject.keywordPlus | STOMACH | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | COMMUNITIES | - |
dc.subject.keywordAuthor | Gastric cancer | - |
dc.subject.keywordAuthor | gastric microbiota | - |
dc.subject.keywordAuthor | Helicobacter pylori | - |
dc.subject.keywordAuthor | nitrate-reducing bacteria | - |
dc.subject.keywordAuthor | nitrosating bacteria | - |
dc.subject.keywordAuthor | pyrosequencing | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/hel.12293 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.