Ampicillin/Sulbactam-induced Hemo- lytic Anemia Manifested as Hyperbiliru- binemia in a Preterm Infantopen access
- Authors
- Roh. Joo-Hyung; Yun, Hey-Suk; Park, Hyun-Kyung; Lee, Hyun Ju; Kim, Chang-Ryul; Han, Tae-Hee
- Issue Date
- Sep-2016
- Publisher
- 대한주산의학회
- Keywords
- Ampicillin-sulbactam; Hemolytic anemia; Preterm infant
- Citation
- Perinatology, v.27, no.3, pp.190 - 193
- Indexed
- KCI
- Journal Title
- Perinatology
- Volume
- 27
- Number
- 3
- Start Page
- 190
- End Page
- 193
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/153991
- DOI
- 10.14734/PN.2016.27.3.190
- ISSN
- 2508-4887
- Abstract
- A female was born at 36+5 weeks of gestation with a birth weight of 2,120 g. Apgar score was 7 at 1 minute and 9 at 5 minutes. Shortly after birth, tachypnea, chest retraction, and a severe build-up of oral secretions were noted. Her blood type was A+ and initial hemoglobin was 17.5 g/dl. Her mother was A+ blood type. Ampicillin/Sulbactam and gentamicin were started empirically. At 8th day of admission, laboratory results showed hemolytic anemia. Exchange transfusion was performed along with intravenous immunoglobulin and hydrocortisone. After 2 days, the patient’s clinical and laboratory conditions improved. Column hemagglutination assay revealed that the patient’s hemolysis was due to ampicillin/sulbactam.
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