Diagnostic Value of the Serum Anti-Toxocara IgG Titer for Ocular Toxocariasis in Patients with Uveitis at a Tertiary Hospital in Korea.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bae, Ki Woong | - |
dc.contributor.author | Ahn, Seong Joon | - |
dc.contributor.author | Park, Kyu Hyung | - |
dc.contributor.author | Woo, Se Joon | - |
dc.date.accessioned | 2022-07-15T09:48:09Z | - |
dc.date.available | 2022-07-15T09:48:09Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2016-08 | - |
dc.identifier.issn | 1011-8942 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154120 | - |
dc.description.abstract | Purpose This study evaluated the prevalence of ocular toxocariasis (OT) in patients with uveitis of unknown etiology who visited a tertiary hospital in South Korea and assessed the success of serum anti-Toxocara immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA) as a diagnostic test for OT. Methods The records of consecutive patients with intraocular inflammation of unknown etiology were reviewed. All participants underwent clinical and laboratory investigations, including ELISA for serum anti-Toxocara IgG. OT was diagnosed based on typical clinical findings. Clinical characteristics, seropositivity, and IgG titers were compared between patients diagnosed with OT and non-OT uveitis. The seropositivity and the diagnostic value of anti-Toxocara IgG was investigated among patients with different types of uveitis. Results Of 238 patients with uveitis of unknown etiology, 71 (29.8%) were diagnosed with OT, and 80 (33.6%) had positive ELISA results for serum anti-Toxocara IgG. The sensitivity and specificity of the ELISA test were 91.5% (65 / 71) and 91.0% (152 / 167), respectively. The positive predictive value of the serum anti-Toxocara IgG assay was 81.3%. Among patients with anterior, intermediate, posterior, and panuveitis, the prevalence rates of OT were 8.3%, 47.1%, 44.8%, and 7.1%, respectively; the seropositivity percentages were 18.1%, 47.1%, 43.7%, and 17.9%; and the positive predictive values were 38.5%, 95.8%, 92.1%, and 40.0%. The serum anti-Toxocara IgG titer also significantly decreased following albendazole treatment. Conclusions OT is a common cause of intraocular inflammation in the tertiary hospital setting. Considering that OT is more prevalent in intermediate and posterior uveitis, and that the positive predictive value of the anti-Toxocara IgG assay is high, a routine test for anti-Toxocara IgG might be necessary for Korean patients with intermediate and posterior uveitis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한안과학회 | - |
dc.title | Diagnostic Value of the Serum Anti-Toxocara IgG Titer for Ocular Toxocariasis in Patients with Uveitis at a Tertiary Hospital in Korea. | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ahn, Seong Joon | - |
dc.identifier.doi | 10.3341/kjo.2016.30.4.258 | - |
dc.identifier.scopusid | 2-s2.0-85015355150 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF OPHTHALMOLOGY, v.30, no.4, pp.258 - 264 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF OPHTHALMOLOGY | - |
dc.citation.title | KOREAN JOURNAL OF OPHTHALMOLOGY | - |
dc.citation.volume | 30 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 258 | - |
dc.citation.endPage | 264 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.identifier.kciid | ART002130676 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | antiidiotypic antibody | - |
dc.subject.keywordPlus | immunoglobulin G | - |
dc.subject.keywordAuthor | Enzyme-linked immunosorbent assay | - |
dc.subject.keywordAuthor | Toxocariasis | - |
dc.subject.keywordAuthor | Uveitis | - |
dc.identifier.url | https://www.ekjo.org/journal/view.php?doi=10.3341/kjo.2016.30.4.258 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.