Anaerobic Bacteremia: Impact of Inappropriate Therapy on Mortality
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jieun | - |
dc.contributor.author | Lee, Yangsoon | - |
dc.contributor.author | Park, Yongjung | - |
dc.contributor.author | Kim, Myungsook | - |
dc.contributor.author | Choi, Jun Yong | - |
dc.contributor.author | Yong, Dongeun | - |
dc.contributor.author | Jeong, Seok Hoon | - |
dc.contributor.author | Lee, Kyungwon | - |
dc.date.accessioned | 2022-07-15T16:10:40Z | - |
dc.date.available | 2022-07-15T16:10:40Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2016-06 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154515 | - |
dc.description.abstract | Background: Investigation on incidence and mortality of anaerobic bacteremia (AB) is clinically relevant in spite of its infrequent occurrence and not often explored, which report varies according to period and institutions. Therefore, it is necessary to analyze the incidence and risk factors related to mortality and assess clinical outcomes of AB in current aspect. Materials and Methods: Characteristics of AB patients and anaerobic bacteria from blood culture at a university hospital in 2012 were reviewed retrospectively. The correlation between risk factors and 28-day patient mortality was analyzed. Results: A total of 70 non-duplicated anaerobic bacteria were isolated from blood of 70 bacteremia patients in 2012. The history of cardiovascular disease as host's risk factor was statistically significant (P = 0.0344) in univariate and multivariate analysis. Although the inappropriate therapy was not statistically significant in univariate and multivariate analysis, the survival rate of bacteremia was significantly worse in patients who had inappropriate therapy compared with those underwent appropriate therapy (hazard ratio, 5.4; 95% confidence interval, 1.7-16.9; P = 0.004). The most frequently isolated organism was Bacteroides fragilis (32 isolates, 46%), followed by Bacteroides thetaiotaomicron (10, 14 %), and non-perfringens Clostridium (7, 10%). Conclusion: The incidence of AB in 2012 was 2.3% (number of AB patients per 100 positive blood culture patients) and the mortality rate in patients with clinically significant AB was 21.4%. In addition, AB was frequently noted in patients having malignancy and the survival rate of AB was significantly worse in patients who received inappropriate therapy compared with those underwent appropriate therapy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC CHEMOTHERAPY | - |
dc.title | Anaerobic Bacteremia: Impact of Inappropriate Therapy on Mortality | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Yangsoon | - |
dc.identifier.doi | 10.3947/ic.2016.48.2.91 | - |
dc.identifier.scopusid | 2-s2.0-84982958238 | - |
dc.identifier.wosid | 000382493200004 | - |
dc.identifier.bibliographicCitation | INFECTION AND CHEMOTHERAPY, v.48, no.2, pp.91 - 98 | - |
dc.relation.isPartOf | INFECTION AND CHEMOTHERAPY | - |
dc.citation.title | INFECTION AND CHEMOTHERAPY | - |
dc.citation.volume | 48 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 98 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002123708 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.subject.keywordPlus | CLINICAL-SIGNIFICANCE | - |
dc.subject.keywordPlus | BLOOD CULTURES | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordAuthor | Anaerobic bacteremia | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Survival rate | - |
dc.subject.keywordAuthor | Inappropriate therapy | - |
dc.identifier.url | https://icjournal.org/DOIx.php?id=10.3947/ic.2016.48.2.91 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.