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Chitosan/poly-γ-glutamic acid nanoparticles improve the solubility of lutein
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hong, Da Young | - |
| dc.contributor.author | Lee, Ji-Soo | - |
| dc.contributor.author | Lee, Hyeon Gyu | - |
| dc.date.accessioned | 2022-07-15T17:55:48Z | - |
| dc.date.available | 2022-07-15T17:55:48Z | - |
| dc.date.issued | 2016-04 | - |
| dc.identifier.issn | 0141-8130 | - |
| dc.identifier.issn | 1879-0003 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154852 | - |
| dc.description.abstract | The aim of this study was to improve the solubility of lutein through the use of chitosan (CS)/poly-γ-glutamic acid (γ-PGA) nanoencapsulation. In terms of redispersibility, water-soluble chitosan (WsCS)/γ-PGA nanoparticles (NPs) were better than insoluble chitosan (InCS)/γ-PGA NPs. The lutein-loaded WsCS/γ-PGA NP has a spherical form with a size around 200 nm and a narrow size distribution (PDI < 0.1). Solubility measures showed that nanoencapsulation of lutein into WsCS/γ-PGA NPs resulted in a significant 12-fold higher solubility compared to that of non-nanoencapsulated lutein (p < 0.05). The redispersibility index of the lutein-loaded NPs was 1.01, indicating that they were completely reconstituted into aqueous solution as same as original aqueous solution. These results suggest that WsCS/γ-PGA nanoencapsulation can be used to enhance the solubility of lutein and other poorly water-soluble compounds. | - |
| dc.format.extent | 7 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | Elsevier BV | - |
| dc.title | Chitosan/poly-γ-glutamic acid nanoparticles improve the solubility of lutein | - |
| dc.type | Article | - |
| dc.publisher.location | 네델란드 | - |
| dc.identifier.doi | 10.1016/j.ijbiomac.2015.12.044 | - |
| dc.identifier.scopusid | 2-s2.0-84952326540 | - |
| dc.identifier.wosid | 000370886800002 | - |
| dc.identifier.bibliographicCitation | International Journal of Biological Macromolecules, v.85, pp 9 - 15 | - |
| dc.citation.title | International Journal of Biological Macromolecules | - |
| dc.citation.volume | 85 | - |
| dc.citation.startPage | 9 | - |
| dc.citation.endPage | 15 | - |
| dc.type.docType | Article | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalResearchArea | Polymer Science | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
| dc.relation.journalWebOfScienceCategory | Polymer Science | - |
| dc.subject.keywordPlus | ORAL INSULIN DELIVERY | - |
| dc.subject.keywordPlus | SOLID DISPERSIONS | - |
| dc.subject.keywordPlus | BIOAVAILABILITY | - |
| dc.subject.keywordPlus | STABILITY | - |
| dc.subject.keywordPlus | QUALITY | - |
| dc.subject.keywordPlus | DRUGS | - |
| dc.subject.keywordPlus | SIZE | - |
| dc.subject.keywordAuthor | Lutein | - |
| dc.subject.keywordAuthor | Nanoparticle | - |
| dc.subject.keywordAuthor | Solubility | - |
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Related Researcher
- Lee, Hyeon Gyu
- COLLEGE OF HUMAN ECOLOGY (DEPARTMENT OF FOOD & NUTRITION)