Effect of Photofunctionalization on Ti6Al4V Screw Stability Placed in Segmental Bone Defects in Rat Femurs
DC Field | Value | Language |
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dc.contributor.author | Hirota, Makoto | - |
dc.contributor.author | Tanaka, Miyuki | - |
dc.contributor.author | Ishijima, Manabu | - |
dc.contributor.author | Iwasaki, Chika | - |
dc.contributor.author | Park, Wonhee | - |
dc.contributor.author | Ogawa, Takahiro | - |
dc.date.accessioned | 2022-07-15T18:01:19Z | - |
dc.date.available | 2022-07-15T18:01:19Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0278-2391 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154885 | - |
dc.description.abstract | Purpose: Ultraviolet-mediated photofunctionalization is a new technology to improve bone and titanium integration. We hypothesized that photofunctionalization would enhance the stability of titanium screws used for segmental bone defects. Materials and Methods: Disks were prepared of a titanium alloy (Ti6Al4V) for an in vitro study to evaluate the attachment, proliferation, and differentiation of osteoblasts. Commercially available Ti6Al4V screws were used in vivo. Segmental bone defects were created in rat femurs as an immediate loading reconstruction model. The defects were reconstructed with commercially available titanium plates and Ti6Al4V screws, with or without photofunctionalization. The screw survival rates and mechanical stability were evaluated at 2 and 4 weeks, and the bone formation around the screws was analyzed. Results: Osteoblasts showed greater attachment, proliferation, and differentiation on the photofunctionalized Ti6Al4V disks. Photofunctionalized screws had significantly greater survival rates and mechanical stability at 2 and 4 weeks. The bone formation around the photofunctionalized screws was significantly greater than that around the untreated screws at 4 weeks. Conclusions: The results of the present study have demonstrated the efficacy of photofunctionalization on enhancing the survival and stability of Ti6Al4V screws under a loaded condition in the reconstruction of segmental defects. This was associated with increased bioactivity and bone formation around the photofunctionalized Ti6Al4V material. (C) 2016 American Association of Oral and Maxillofacial Surgeons | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | W. B. Saunders Co., Ltd. | - |
dc.title | Effect of Photofunctionalization on Ti6Al4V Screw Stability Placed in Segmental Bone Defects in Rat Femurs | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Wonhee | - |
dc.identifier.doi | 10.1016/j.joms.2015.11.016 | - |
dc.identifier.scopusid | 2-s2.0-84981249601 | - |
dc.identifier.wosid | 000373090400031 | - |
dc.identifier.bibliographicCitation | Journal of Oral and Maxillofacial Surgery, v.74, no.4, pp.861.e1 - 861.e16 | - |
dc.relation.isPartOf | Journal of Oral and Maxillofacial Surgery | - |
dc.citation.title | Journal of Oral and Maxillofacial Surgery | - |
dc.citation.volume | 74 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 861.e1 | - |
dc.citation.endPage | 861.e16 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dentistry, Oral Surgery & Medicine | - |
dc.relation.journalWebOfScienceCategory | Dentistry, Oral Surgery & Medicine | - |
dc.subject.keywordPlus | MANDIBULAR RECONSTRUCTION | - |
dc.subject.keywordPlus | IMPLANT STABILITY | - |
dc.subject.keywordPlus | TITANIUM | - |
dc.subject.keywordPlus | PLATES | - |
dc.subject.keywordPlus | INTEGRATION | - |
dc.subject.keywordPlus | CONTACT | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | TIME | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0278239115015530?via%3Dihub | - |
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