Relationship of functional disability after a recent stroke with recurrent stroke risk
DC Field | Value | Language |
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dc.contributor.author | Park, Jong Ho | - |
dc.contributor.author | Ovbiagele, Bruce | - |
dc.date.accessioned | 2022-07-15T18:25:21Z | - |
dc.date.available | 2022-07-15T18:25:21Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2016-02 | - |
dc.identifier.issn | 1351-5101 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/155110 | - |
dc.description.abstract | Background and purpose: Post-stroke disability status is primarily focused on recovery prognostication but the influence of post-stroke disability on future vascular risk is unknown. The relationship between functional disability after an index stroke and risk of recurrent vascular events was examined. Methods: A cohort analysis of 3680 recent non-cardioembolic, non-to-moderate disabled [modified Rankin Scale (mRS) ≤3] stroke patients aged ≥35 years and followed for 2 years was reviewed. The mRS measured at a median of 35 days after the index stroke was analyzed as a dichotomous variable (mRS 3 vs. ≤2) and in a stepwise manner. Independent associations of post-stroke disability by mRS score with ischaemic stroke (primary outcome), stroke/coronary heart disease/vascular death as major vascular events (secondary outcome) and all-cause death (tertiary outcome) were analyzed. Results: Amongst study participants, 435 (11.8%) had an mRS of 3. Compared with mRS ≤2 as no/slight disability, mRS 3 as moderate disability was associated with a higher risk of stroke (adjusted hazard ratio 1.45, 95% confidence interval 1.06-1.99). Compared with mRS 0, there was a progressively higher independent risk for each of the study outcomes: stroke, mRS 1 (1.42, 0.97-2.08), mRS 2 (1.46, 0.97-2.20), mRS 3 (1.89, 1.20-2.97); major vascular events, mRS 1 (1.31, 1.01-1.70), mRS 2 (1.31, 0.99-1.74), mRS 3 (1.46, 1.06-2.01); and all-cause death, mRS 1 (1.75, 1.03-2.98), mRS 2 (2.49, 1.44-4.31), mRS 3 (2.72, 1.43-5.19). Conclusion: Compared with no/slight disability, moderate disability after a recent stroke is linked to a higher risk of recurrent stroke. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.title | Relationship of functional disability after a recent stroke with recurrent stroke risk | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Jong Ho | - |
dc.identifier.doi | 10.1111/ene.12837 | - |
dc.identifier.scopusid | 2-s2.0-84956576487 | - |
dc.identifier.wosid | 000368797100031 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF NEUROLOGY, v.23, no.2, pp.361 - 367 | - |
dc.relation.isPartOf | EUROPEAN JOURNAL OF NEUROLOGY | - |
dc.citation.title | EUROPEAN JOURNAL OF NEUROLOGY | - |
dc.citation.volume | 23 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 361 | - |
dc.citation.endPage | 367 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | MODIFIED RANKIN SCALE | - |
dc.subject.keywordPlus | ISCHEMIC-STROKEHE | - |
dc.subject.keywordPlus | ART-DISEASE | - |
dc.subject.keywordPlus | VITAMIN-D | - |
dc.subject.keywordPlus | DEPRESSION | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | FUTURE | - |
dc.subject.keywordAuthor | Disability | - |
dc.subject.keywordAuthor | Ischaemic stroke | - |
dc.subject.keywordAuthor | Modified Rankin Scale | - |
dc.subject.keywordAuthor | Risk | - |
dc.subject.keywordAuthor | Vascular outcome | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/ene.12837 | - |
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