Biocompatible responsive polypyrrole/GO nanocomposite coatings for biomedical applications

Abstract

Hybrid implant coating materials composed of at least two constituents of different chemistry, functionality, and biocompatibility have attracted attention in a wide range of biomedical applications. One-step electrosynthesis of polypyrrole (PPy)/graphene oxide (GO) nanocomposites on 316L SS implants was achieved by electropolymerization of pyrrole using different amounts of GO. Possible interaction between the PPy chain and GO nanosheet was examined by structural characterizations including UV-visible, X-ray diffraction, Raman, and X-ray photoelectron spectroscopy analyses. Morphological study by scanning electron microscopy and transmission electron microscopy confirmed dispersion of the GO nanosheets within the PPy matrix. Further, in vitro cell culture studies were carried out using MG-63 human osteoblast cells to estimate the biocompatibility of PPy/GO coatings. Noticeable improvements in surface protective and biocompatibility performance suggest possible application as a bioactive coating material on 316L SS implants for biomedical fields.