Prognostic Significance of 1-Year Serum Albumin Levels Within the Normal Range After Kidney Transplantation
DC Field | Value | Language |
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dc.contributor.author | Oh, Il Hwan | - |
dc.contributor.author | Park, Joon-Sung | - |
dc.contributor.author | Lee, Chang Hwa | - |
dc.contributor.author | Kang, Chong Myung | - |
dc.contributor.author | Kim, Gheun-Ho | - |
dc.date.accessioned | 2022-07-15T20:22:31Z | - |
dc.date.available | 2022-07-15T20:22:31Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2015-11 | - |
dc.identifier.issn | 0160-564X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/155993 | - |
dc.description.abstract | Hypoalbuminemia is associated with poor outcomes in kidney transplantation (KT). However, what level is optimal in serum albumin is not clear for the long-term prognosis. To determine whether the long-term outcomes are different even between the normal ranges of serum albumin after KT, we analyzed data from 404 renal allograft recipients whose 1-year post-transplant serum albumin levels were within the normal limits (3.5-5.5g/dL). During a follow-up of 122 +/- 56 months, 97 graft losses, 20 patient deaths, and 50 cardiovascular (CV) events occurred. Based on 1-year serum albumin levels, the patients were divided into high normal (4.6g/dL, n=209) and low normal (<4.6g/dL, n=195) groups. Kaplan-Meier analyses revealed that the low normal group had poorer allograft survival (P=0.01), patient survival (P<0.001), and CV event-free survival (P<0.001) than the high normal group. Cox regression analysis confirmed that 1-year serum albumin was inversely associated with the risk of graft loss (hazard ratio [HR] 0.414, 95% confidence interval [CI] 0.200-0.856), patient death (HR 0.097, 95% CI 0.019-0.484), and CV events (HR 0.228, 95% CI 0.074-0.702). In conclusion, a relatively low 1-year post-transplant serum albumin level within the normal limits (<4.6g/dL) significantly predicts poor long-term outcomes. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Prognostic Significance of 1-Year Serum Albumin Levels Within the Normal Range After Kidney Transplantation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Joon-Sung | - |
dc.contributor.affiliatedAuthor | Lee, Chang Hwa | - |
dc.contributor.affiliatedAuthor | Kim, Gheun-Ho | - |
dc.identifier.doi | 10.1111/aor.12473 | - |
dc.identifier.scopusid | 2-s2.0-84945480490 | - |
dc.identifier.wosid | 000363452600008 | - |
dc.identifier.bibliographicCitation | ARTIFICIAL ORGANS, v.39, no.11, pp.965 - 972 | - |
dc.relation.isPartOf | ARTIFICIAL ORGANS | - |
dc.citation.title | ARTIFICIAL ORGANS | - |
dc.citation.volume | 39 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 965 | - |
dc.citation.endPage | 972 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | CORONARY-HEART-DISEASE | - |
dc.subject.keywordPlus | GLOMERULAR-FILTRATION-RATE | - |
dc.subject.keywordPlus | FACTOR INTERVENTION TRIAL | - |
dc.subject.keywordPlus | ACUTE-PHASE PROTEINS | - |
dc.subject.keywordPlus | STAGE RENAL-DISEASE | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | DIALYSIS PATIENTS | - |
dc.subject.keywordPlus | CATABOLIC RATE | - |
dc.subject.keywordAuthor | Albumin | - |
dc.subject.keywordAuthor | Kidney transplantation | - |
dc.subject.keywordAuthor | Allograft survival | - |
dc.subject.keywordAuthor | Patient survival | - |
dc.subject.keywordAuthor | Cardiovascular mortality | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/aor.12473 | - |
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