Neurologic Symptom Severity after a Recent Noncardioembolic Stroke and Recurrent Vascular Risk.
DC Field | Value | Language |
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dc.contributor.author | Park, Jong-Ho | - |
dc.contributor.author | Ovbiagele, Bruce | - |
dc.date.accessioned | 2022-07-15T22:50:57Z | - |
dc.date.available | 2022-07-15T22:50:57Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2015-05 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/157222 | - |
dc.description.abstract | Background: There is a well-established relation of symptom severity with functional status and mortality after an index stroke. However, little is known about the impact of symptom severity of a recent index stroke on risk of recurrent vascular events. Methods: We reviewed the data set of a multicenter trial involving 3680 recent non-cardioembolic stroke patients aged 35 years or older and followed for 2 years. Independent associations of stroke severity (as measured by National Institutes of Health Stroke Scale [NIHSS] score) with recurrent stroke (primary outcome) and stroke/coronary heart disease (CHD)/vascular death (secondary outcome) were analyzed. NIHSS score was analyzed as a dichotomous (<4 versus >= 4) and a continuous variable. Results: Among study subjects, 550 (15%) had NIHSS scores of 4 or more (overall scores ranged from 0 to 18, median score was 1 [25th-75th percentile 0-2]). NIHSS was measured at a median of 35 days after the index stroke. After adjusting for multiple covariates, NIHSS of 4 or more was independently linked to a higher risk of recurrent stroke (hazard ratio [HR], 1.37; 95% confidence interval [CI], 1.01-1.84) and risk of stroke/CHD/vascular death (HR, 1.32; 95% CI, 1.07-1.64). Analysis of NIHSS score as a continuous variable also showed a higher risk of recurrent stroke (HR, 1.06; 95% CI, 1.00-1.12) and stroke/CHD/vascular death (HR, 1.05; 95% CI, 1.01-1.09) with increasing index stroke symptom severity. Conclusions: Greater residual symptom severity after a recent stroke is associated with higher risk of recurrent vascular events. Future studies are needed to confirm this relationship and to clarify its underlying mechanisms. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Neurologic Symptom Severity after a Recent Noncardioembolic Stroke and Recurrent Vascular Risk. | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Jong-Ho | - |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2014.12.033 | - |
dc.identifier.scopusid | 2-s2.0-84928273759 | - |
dc.identifier.wosid | 000353185600027 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.24, no.5, pp.1032 - 1037 | - |
dc.relation.isPartOf | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.title | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.volume | 24 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1032 | - |
dc.citation.endPage | 1037 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | ISCHEMIC-STROKE | - |
dc.subject.keywordPlus | DEPRESSION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | INFARCTION | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | SCALE | - |
dc.subject.keywordPlus | SCORE | - |
dc.subject.keywordAuthor | National Institutes of Health Stroke Scale | - |
dc.subject.keywordAuthor | ischemic stroke | - |
dc.subject.keywordAuthor | vascular events | - |
dc.subject.keywordAuthor | risk | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1052305714006466?via%3Dihub | - |
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