Steroid plus antiviral treatment for Bell’s palsy
DC Field | Value | Language |
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dc.contributor.author | Kang, H. M. | - |
dc.contributor.author | Jung, S. Y | - |
dc.contributor.author | Byun, J. Y. | - |
dc.contributor.author | Park, M. S. | - |
dc.contributor.author | Yeo, S. G. | - |
dc.date.accessioned | 2022-07-15T22:51:48Z | - |
dc.date.available | 2022-07-15T22:51:48Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2015-05 | - |
dc.identifier.issn | 0954-6820 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/157230 | - |
dc.description.abstract | Objectives: The effectiveness of antiviral agents for the treatment of Bell's palsy is uncertain. We evaluated whether a steroid with an antiviral agent (S + A group) provided better recovery outcomes than a steroid alone (S group) in patients with Bell's palsy. Subjects and design: A total of 1342 patients diagnosed with Bell's palsy who visited the Kyung Hee Medical Center in Seoul, Korea, from 2002 to 2012 were included in this study. Patients in the S + A group were treated with prednisolone and antiviral agents (n = 569) and those in the S group with prednisolone alone (n = 773). Outcomes were measured using the House-Brackmann (HB) scale according to age, initial disease severity, electroneurography (ENoG) findings and underlying comorbidities. Results: The rate of recovery (HB grades I and II) with initially severe Bell's palsy (HB grades V and VI) was higher in the S + A than in the S group (P = 0.001). However, the rates of recovery were similar with initially moderate palsy (HB grades II-IV) (P = 0.502). In patients classified according to age and ENoG-determined severity of palsy, the overall recovery rate was higher in the S + A than in the S group, but the differences were not statistically significant (P > 0.05 for both). The recovery rate without diabetes mellitus (DM) and hypertension (HTN) was higher in the S + A group than in the S group (P = 0.031). But in the patients with HTN and DM, the difference in recovery rates between the S + A and S groups was not statistically significant (P = 0.805). Conclusions: Treatment with a steroid plus antiviral agent resulted in significantly higher recovery rates than steroid therapy alone in patients with initially severe Bell's palsy and without either HTN or DM, and a nonsignificant trend towards higher recovery rates in all patients with Bell's palsy in this study. Antiviral agents may therefore help in the treatment of Bell's palsy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.title | Steroid plus antiviral treatment for Bell’s palsy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, S. Y | - |
dc.identifier.doi | 10.1111/joim.12288 | - |
dc.identifier.scopusid | 2-s2.0-84927020939 | - |
dc.identifier.wosid | 000352801300004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INTERNAL MEDICINE, v.277, no.5, pp.532 - 539 | - |
dc.relation.isPartOf | JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 277 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 532 | - |
dc.citation.endPage | 539 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | PERIPHERAL FACIAL PALSY | - |
dc.subject.keywordPlus | RAMSAY-HUNT-SYNDROME | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | PREDNISOLONE | - |
dc.subject.keywordPlus | ACYCLOVIR | - |
dc.subject.keywordPlus | ETIOLOGY | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordAuthor | age | - |
dc.subject.keywordAuthor | antivirals | - |
dc.subject.keywordAuthor | Bell&apos | - |
dc.subject.keywordAuthor | s palsy | - |
dc.subject.keywordAuthor | electroneurography | - |
dc.subject.keywordAuthor | severity | - |
dc.subject.keywordAuthor | steroid | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/joim.12288 | - |
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