Three-month Treatment Response and Exacerbation in Chronic Obstructive Pulmonary Disease
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jung Su | - |
dc.contributor.author | Rhee, Chin Kook | - |
dc.contributor.author | Yoo, Kwang Ha | - |
dc.contributor.author | Lee, Ji-Hyun | - |
dc.contributor.author | Yoon, Ho Il | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | Kim, Woo Jin | - |
dc.contributor.author | Lee, JinHwa | - |
dc.contributor.author | Lim, Seong Yong | - |
dc.contributor.author | Park, Tai Sun | - |
dc.contributor.author | Lee, Jae Seung | - |
dc.contributor.author | Lee, Sei Won | - |
dc.contributor.author | Lee, Sang-Do | - |
dc.contributor.author | Oh, Yeon-Mok | - |
dc.date.accessioned | 2022-07-16T00:55:38Z | - |
dc.date.available | 2022-07-16T00:55:38Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/158108 | - |
dc.description.abstract | The aim of this study was to investigate relationships between acute exacerbation and Forced Expiratory Volume 1 second (FEV1) improvement after treatment with combined long-acting beta-agonist (LABA) and inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD). A total of 137 COPD patients were classified as responders or nonresponders according to FEV1 improvement after 3 months of LABA/ICS treatment in fourteen referral hospitals in Korea. Exacerbation occurrence in these two subgroups was compared over a period of 1 yr. Eighty of the 137 COPD patients (58.4%) were classified as responders and 57 (41.6%) as nonresponders. Acute exacerbations occurred in 25 patients (31.3%) in the responder group and in 26 patients (45.6%) in the nonresponder group (P = 0.086). FEV1 improvement after LABA/ICS treatment was a significant prognostic factor for fewer acute exacerbations in a multivariate Cox proportional hazard model adjusted for age, sex, FEV1, smoking history, 6 min walk distance, body mass index, exacerbation history in the previous year, and dyspnea scale. Three-month treatment response to LABA/ICS might be a prognostic factor for the occurrence of acute exacerbation in COPD patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | Three-month Treatment Response and Exacerbation in Chronic Obstructive Pulmonary Disease | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hyung | - |
dc.contributor.affiliatedAuthor | Park, Tai Sun | - |
dc.identifier.doi | 10.3346/jkms.2015.30.1.54 | - |
dc.identifier.scopusid | 2-s2.0-84951083200 | - |
dc.identifier.wosid | 000351763000007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.30, no.1, pp.54 - 59 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 30 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 54 | - |
dc.citation.endPage | 59 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001956015 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | LUNG-FUNCTION DECLINE | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | COPD | - |
dc.subject.keywordPlus | TRIALS | - |
dc.subject.keywordPlus | AGONIST | - |
dc.subject.keywordPlus | FEV1 | - |
dc.subject.keywordAuthor | Pulmonary Disease | - |
dc.subject.keywordAuthor | Chronic Obstructive | - |
dc.subject.keywordAuthor | Forced Expiratory Volume | - |
dc.subject.keywordAuthor | Disease Progression | - |
dc.identifier.url | https://jkms.org/DOIx.php?id=10.3346/jkms.2015.30.1.54 | - |
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