Prospective Measurement of Urinary Microalbumin in Living Kidney Donor Nephrectomy: Toward Understanding the Renal Functional Recovery Period
DC Field | Value | Language |
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dc.contributor.author | Yoon, YOUNG EUN | - |
dc.contributor.author | Lee, Kwang Suk | - |
dc.contributor.author | Choi, Kyung Hwa | - |
dc.contributor.author | Kim, Kwang Hyun | - |
dc.contributor.author | Yang, Seung Choul | - |
dc.contributor.author | Han, Woong Kyu | - |
dc.date.accessioned | 2022-07-16T02:34:01Z | - |
dc.date.available | 2022-07-16T02:34:01Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 0022-5347 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/158890 | - |
dc.description.abstract | Purpose: We determined the clinical implications of perioperative urinary microalbumin excretion in relation to renal function after living donor nephrectomy. Materials and Methods: Between August 2010 and January 2013, 259 donors undergoing live donor nephrectomy were enrolled in the study. The donor urinary albumin-to-creatinine ratio was measured perioperatively, and changes in perioperative urinary albumin-to-creatinine ratio and the implications of preoperative microalbuminuria (urinary albumin-to-creatinine ratio 30 mg/gm or greater) were investigated. The relationships between perioperative urinary albumin-to-creatinine ratio and recovery of renal function and implantation biopsy histology were also analyzed. Results: Mean +/- SD preoperative urinary albumin-to-creatinine ratio was 7.1 +/- 12.7 mg/gm. The urinary albumin-to-creatinine ratio was increased after 1 day (24.7 +/- 18.9 mg/gm, p < 0.001) and stabilized after 1 month (10.3 +/- 10.7 mg/gm, p < 0.001). Preoperative microalbuminuria was not associated with perioperative estimated glomerular filtration rate during a followup period of 6 months but was associated with histological abnormalities. Donors with a higher urinary albumin-to-creatinine ratio before donation, even in the normal range, consistently had an increased postoperative urinary albumin-to-creatinine ratio. A ROC curve analysis showed that age, preoperative estimated glomerular filtration rate and 1-month postoperative urinary albumin-to-creatinine ratio were highly predictive of delayed recovery of renal function (AUC 0.884, p < 0.001). The 1-month postoperative urinary albumin-to-creatinine ratio was associated with delayed recovery of renal function (OR 1.05 for each 0.1 mg/gm increase, p = 0.021). Conclusions: Donors with higher preoperative urinary albumin-to-creatinine ratio levels require close observation because there is a greater possibility of microalbuminuria developing after donation even if the ratio is within the normal range. A higher urinary albumin-to-creatinine ratio was also associated with delayed recovery of renal function and histological abnormalities. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Prospective Measurement of Urinary Microalbumin in Living Kidney Donor Nephrectomy: Toward Understanding the Renal Functional Recovery Period | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, YOUNG EUN | - |
dc.identifier.doi | 10.1016/j.juro.2014.03.106 | - |
dc.identifier.scopusid | 2-s2.0-84921970178 | - |
dc.identifier.wosid | 000342113900060 | - |
dc.identifier.bibliographicCitation | JOURNAL OF UROLOGY, v.192, no.4, pp.1172 - 1177 | - |
dc.relation.isPartOf | JOURNAL OF UROLOGY | - |
dc.citation.title | JOURNAL OF UROLOGY | - |
dc.citation.volume | 192 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1172 | - |
dc.citation.endPage | 1177 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | MINILAPAROTOMY SURGERY | - |
dc.subject.keywordPlus | ALBUMINURIA | - |
dc.subject.keywordPlus | PROTEINURIA | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | HISTOLOGY | - |
dc.subject.keywordPlus | BIOPSY | - |
dc.subject.keywordPlus | RATIO | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordAuthor | kidney transplantation | - |
dc.subject.keywordAuthor | albuminuria | - |
dc.subject.keywordAuthor | delayed graft function | - |
dc.subject.keywordAuthor | nephrectomy | - |
dc.subject.keywordAuthor | living donors | - |
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