Clinical safety of endoscopic submucosal dissection compared with surgery in elderly patients with early gastric cancer: a propensity-matched analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Chan Hyuk | - |
dc.contributor.author | Lee, Hyuk | - |
dc.contributor.author | Kim, Dong Wook | - |
dc.contributor.author | Chung, Hyunsoo | - |
dc.contributor.author | Park, Jun Chul | - |
dc.contributor.author | Shin, Sung Kwan | - |
dc.contributor.author | Hyung, Woo Jin | - |
dc.contributor.author | Lee, Sang Kil | - |
dc.contributor.author | Lee, Yong Chan | - |
dc.contributor.author | Noh, Sung Hoon | - |
dc.date.accessioned | 2022-07-16T02:53:34Z | - |
dc.date.available | 2022-07-16T02:53:34Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 0016-5107 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159034 | - |
dc.description.abstract | Background: Little is known about the clinical and oncologic outcomes of endoscopic submucosal dissection (ESD) compared with surgery in elderly patients with early gastric cancer (EGC). Objective: To evaluate the clinical and oncologic outcomes of ESD compared with surgery in elderly patients with EGC of an expanded indication. Design: Retrospective study with propensity-matched analysis. Setting: University-affiliated tertiary-care hospital, Seoul, South Korea. Patients: A total of 518 patients 70 years of age or older with initial-onset EGC. Interventions: ESD and surgery. Main Outcome Measurements: Clinical outcomes, disease-free survival, and overall survival. Results: In a propensity-matched analysis of 132 pairs, the length of hospital stay of the ESD group was shorter than that of the surgery group (median [interquartile range], 4 [3-4] vs 9 [7-11] days; P<.001). Intensive care unit admission occurred in the surgery group only (7 patients [5.3%]). Two surgery-related deaths occurred in the surgery group (1 splenic artery bleeding and 1 anastomosis site leakage). During follow-up, metachronous lesions developed more often in the ESD group than in the surgery group (12 vs 2 lesions, P=.004). All recurred lesions were successfully treated endoscopically except for 3 patients who refused additional treatment. Overall survival did not differ between the 2 groups (P=.280). Limitations: Nonrandomized, retrospective study. Conclusions: ESD is a safe procedure in elderly patients with EGC. Although the risk of metachronous lesions is higher in patients who undergo ESD than in those who undergo surgery, overall survival did not differ between the patients who undergo ESD and surgery. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.title | Clinical safety of endoscopic submucosal dissection compared with surgery in elderly patients with early gastric cancer: a propensity-matched analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Chan Hyuk | - |
dc.identifier.doi | 10.1016/j.gie.2014.04.042 | - |
dc.identifier.scopusid | 2-s2.0-84922417802 | - |
dc.identifier.wosid | 000342166400007 | - |
dc.identifier.bibliographicCitation | GASTROINTESTINAL ENDOSCOPY, v.80, no.4, pp.599 - 609 | - |
dc.relation.isPartOf | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.title | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.volume | 80 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 599 | - |
dc.citation.endPage | 609 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | LONG-TERM OUTCOMES | - |
dc.subject.keywordPlus | UPPER GASTROINTESTINAL ENDOSCOPY | - |
dc.subject.keywordPlus | RETROSPECTIVE COHORT | - |
dc.subject.keywordPlus | SEDATION METHODS | - |
dc.subject.keywordPlus | RESECTION | - |
dc.subject.keywordPlus | GASTRECTOMY | - |
dc.subject.keywordPlus | NEOPLASIA | - |
dc.subject.keywordPlus | CRITERIA | - |
dc.subject.keywordPlus | ESD | - |
dc.subject.keywordPlus | FEASIBILITY | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0016510714014102?via%3Dihub | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.