Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults
- Authors
- Kang, Ho Song; Lee, Min Won; Paek, Jun Oh; Yu, Hee Joon; Kim, Joung Soo
- Issue Date
- Oct-2014
- Publisher
- WILEY-BLACKWELL
- Citation
- INTERNATIONAL JOURNAL OF DERMATOLOGY, v.53, no.10, pp.1293 - 1298
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF DERMATOLOGY
- Volume
- 53
- Number
- 10
- Start Page
- 1293
- End Page
- 1298
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159043
- DOI
- 10.1111/ijd.12377
- ISSN
- 0011-9059
- Abstract
- Background
Immunotherapy has been used for many years in the treatment of warts. Diphenylcyclopropenone is frequently used as an immunotherapeutic agent.
Methods
A total of 143 patients with 180 cases of warts were included in this study. We divided the patients into two groups: 72 children/adolescents and 71 adults aged 20 and over. We evaluated two types of sensitization reaction, using an erythema and blister index and a pruritus index.
Results
Of the 180 cases of warts, 159 (88.3%) were completely cured: 86 (92.5%) of the 93 cases in children/adolescents and 73 (83.9%) of the 87 cases in adults. The time required for complete cure was 17.72 +/- 2.69 weeks in children/adolescents and 22.92 +/- 2.59 weeks in adults (P < 0.05).
Conclusions
Diphenylcyclopropenone immunotherapy can be used effectively for both children/adolescents and adults. The time required for complete cure is shorter in children/adolescents than in adults.
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