Comparison of the Haas and the Oxford classifications for prediction of renal outcome in patients with IgA nephropathy
DC Field | Value | Language |
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dc.contributor.author | Park, Kyoung Sook | - |
dc.contributor.author | Han, Seung Hyeok | - |
dc.contributor.author | Kie, Jeong Hae | - |
dc.contributor.author | Nam, Ki Heon | - |
dc.contributor.author | Lee, Mi Jung | - |
dc.contributor.author | Lim, Beom Jin | - |
dc.contributor.author | Kwon, Young Eun | - |
dc.contributor.author | Kim, Yung Ly | - |
dc.contributor.author | An, Seong Yeong | - |
dc.contributor.author | Kim, Chan Ho | - |
dc.contributor.author | Doh, Fa Mee | - |
dc.contributor.author | Koo, Hyang Mo | - |
dc.contributor.author | Oh, Hyung Jung | - |
dc.contributor.author | Kang, Shin-Wook | - |
dc.contributor.author | Choi, Kyu Hun | - |
dc.contributor.author | Choi, Kyu Hun | - |
dc.contributor.author | Yoo, Tae-Hyun | - |
dc.date.accessioned | 2022-07-16T06:01:52Z | - |
dc.date.available | 2022-07-16T06:01:52Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2014-02 | - |
dc.identifier.issn | 0046-8177 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/160624 | - |
dc.description.abstract | Pathologic features can provide valuable information for determining prognosis in IgA nephropathy (IgAN). However, it is uncertain whether the Oxford classification, a new classification of IgAN, can predict renal outcome better than previous ones. We conducted a retrospective cohort study in 500 patients with biopsy-proven IgAN between January 2002 and December 2010 to compare the ability of the Haas and the Oxford classifications to predict renal outcome. Primary outcome was a doubling of the baseline serum creatinine concentration (D-SCr). During a mean follow-up of 68 months, 52(10.4%) and 35 (7.0%) developed D-SCr and end-stage renal disease, respectively. There were graded increases in the development of D-SCr in the higher Haas classes. In addition, the primary endpoint of D-SCr occurred more in patients with the Oxford M and T lesions than those without such lesions. In multivariate Cox regression analyses, the Haas class V (HR, 12.19; P = .002) and the Oxford T1 (hazard ratio [HR], 6.68; P < .001) and T2 (HR, 12.16; P < .001) lesions were independently associated with an increased risk of reaching D-SCr. Harrell's C index of each multivariate model with the Haas and the Oxford classification was 0.867 (P = .015) and 0.881 (P = .004), respectively. This was significantly higher than that of model with clinical factors only (C = 0.819). However, there was no difference in C-statistics between the 2 models with the Haas and the Oxford classifications (P = .348). This study suggests that the Haas and the Oxford classifications are comparable in predicting progression of IgAN. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | - |
dc.title | Comparison of the Haas and the Oxford classifications for prediction of renal outcome in patients with IgA nephropathy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kwon, Young Eun | - |
dc.identifier.doi | 10.1016/j.humpath.2013.08.019 | - |
dc.identifier.scopusid | 2-s2.0-84892687716 | - |
dc.identifier.wosid | 000330551300006 | - |
dc.identifier.bibliographicCitation | HUMAN PATHOLOGY, v.45, no.2, pp.236 - 243 | - |
dc.relation.isPartOf | HUMAN PATHOLOGY | - |
dc.citation.title | HUMAN PATHOLOGY | - |
dc.citation.volume | 45 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 236 | - |
dc.citation.endPage | 243 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pathology | - |
dc.relation.journalWebOfScienceCategory | Pathology | - |
dc.subject.keywordPlus | IMMUNOGLOBULIN-A NEPHROPATHY | - |
dc.subject.keywordPlus | CLINICOPATHOLOGICAL CORRELATIONS | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordPlus | KOREAN ADULTS | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | Proteinuria | - |
dc.subject.keywordAuthor | IgA nephropathy | - |
dc.subject.keywordAuthor | Long-term outcome | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0046817713003766?via%3Dihub | - |
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