자가면역 물집 피부질환 환자의 삶의 질Assessment of the Quality of Life in Autoimmune Blistering Skin Disease Patients
- Other Titles
- Assessment of the Quality of Life in Autoimmune Blistering Skin Disease Patients
- Authors
- 문성훈; 권형일; 박현철; 김정은; 고주연; 노영석
- Issue Date
- 2014
- Publisher
- 대한피부과학회
- Keywords
- Autoimmune; Bullous dermatoses; Quality of life (QOL); Skindex-29; Autoimmune blistering diseases
- Citation
- Korean Journal of Dermatology, v.52, no.6, pp.402 - 409
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Journal of Dermatology
- Volume
- 52
- Number
- 6
- Start Page
- 402
- End Page
- 409
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161022
- ISSN
- 0494-4739
- Abstract
- Background: Autoimmune blistering skin diseases such as pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoidand epidermolysis bullosa acquisita substantially affect patientsʼ daily life and psychosocial well-being.
Objective: The aim of this study was to evaluate the quality of life (QOL) in patients with autoimmune blisteringdiseases and to identify the factors that can influence their QOL by comparing them to healthy controls.
Methods: Forty patients with autoimmune blistering skin diseases and 40 healthy controls were interviewed usingthe Korean version of Skindex-29. The study assessed the clinical severity of the disease.
Results: The total, symptom, function, and emotion scores of Skindex-29 were significantly higher in patients withautoimmune blistering skin diseases (35.28, 40.78, 30.57, and 36.67, respectively) than in the healthy controls (6.90,9.38, 5.47, and 6.60, respectively) (p<0.001). Higher disease severity had a negative correlation with QOL in patientswith blistering skin diseases, and QOL was lower when patients had low levels of satisfaction with treatment.
Conclusion: The results show that autoimmune blistering skin diseases can affect patients’ QOL. In addition, diseaseseverity and low satisfaction with treatment are important factors that reduce QOL. Development of new treatmentsshould improve treatment efficacy and the QOL of patients with autoimmune blistering diseases.
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