Blonanserin-induced Mood Alteration in Schizophrenia and Schizoaffective Disorder: Two Casesopen access
- Authors
- Min, Aran; Kim, Daeho
- Issue Date
- Dec-2013
- Publisher
- KOREAN COLL NEUROPSYCHOPHARMACOLOGY
- Keywords
- Blonanserin; Bipolar disorder; Antipsychotic agents; Schizophrenia; Psychotic disorders
- Citation
- CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, v.11, no.3, pp.165 - 167
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
- Volume
- 11
- Number
- 3
- Start Page
- 165
- End Page
- 167
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161326
- DOI
- 10.9758/cpn.2013.11.3.165
- ISSN
- 1738-1088
- Abstract
- We report two outpatients, one with schizophrenia and one with schizoaffective disorder, who developed manic or hypomanic episodes following the initiation of blonanserin during the course of treatment. Blonanserin is a novel antipsychotic that acts as a 5-HT and D2 receptor antagonist. Both patients developed hypomanic episodes within 2 weeks of receiving a small dose (6-8 mg) of blonanserin, and one patient later developed full-blown mania; both episodes ended within 1 rrionth of discontinuing blonanserin, The mood alteration observed in these cases suggests a possible antidepressant effect of blonanserin; thus, clinicians should monitor mood changes when administering this antipsychotic.
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