혈액투석 환자의 단백질 섭취량에 따른 혈중 albumin과 hs-CRP 농도의 비교 연구
DC Field | Value | Language |
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dc.contributor.author | 이예지 | - |
dc.contributor.author | 이연주 | - |
dc.contributor.author | 오일환 | - |
dc.contributor.author | 이창화 | - |
dc.contributor.author | 이상선 | - |
dc.date.accessioned | 2022-07-16T07:11:49Z | - |
dc.date.available | 2022-07-16T07:11:49Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2013-12 | - |
dc.identifier.issn | 2288-3886 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161357 | - |
dc.description.abstract | Protein-energy malnutrition, PEM, and increased hs-CRP level are considered to be associated with increased risk of cardiovascular disease (CVD) in hemodialysis (HD) patients. This is commonly referred to as the vicious circle of malnutrition-infammation-atherosclerosis cardiovascular disease (MIA syndrome) in chronic kidney disease (CKD). Low protein intake can decrease the serum level of albumin and increase infammational markers; further, both low serum albumin and high hs-CRP are independent risk factors for all-cause mortality in HD patients. The aim of this study is comparing the serum levels of albumin and hs-CRP in HD patients according to the protein intake levels. The total number of subjects was 60 hemodialysis patients; they were grouped by dietary protein intake: low protein intake group (LPI, protein intake < 1.0 g/kg IBW, 11 men and 19 women) and adequate protein intake group (API, protein intake > 1.0 g/kg IBW, 12 men and 18 women). Blood biochemical parameters, nutrient intake, and dietary behaviors were compared between the LPI and API groups. The LPI group showed a signifcantly lower serum level of albumin and higher serum level of hs-CRP than the API group (p < 0.05). The LPI group showed a signifcantly lower intake of most nutrients than the API group (p < 0.05). Index of Nutritional Quality of most nutrients of the LPI and API groups were lower than 1.0. Dietary protein intake was positively correlated with the serum level of albumin (r = 0.306, p < 0.05) and negatively correlated with the serum level of hs-CRP (r = -0.435, p < 0.01). The serum level of hs-CRP was negatively correlated with that of albumin (r = -0.393, p < 0.01). According to these result, serum albumin and hs-CRP in HD patients were infuenced by the protein intake levels. To prevent MIA syndrome, it is necessary to improve nutritional status, especially in protein and energy. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | Korean Nutrition Society | - |
dc.title | 혈액투석 환자의 단백질 섭취량에 따른 혈중 albumin과 hs-CRP 농도의 비교 연구 | - |
dc.title.alternative | Comparative study of serum levels of albumin and hs-CRP in hemodialysis patients according to protein intake levels | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 이창화 | - |
dc.identifier.doi | 10.4163/jnh.2013.46.6.521 | - |
dc.identifier.scopusid | 2-s2.0-84896908491 | - |
dc.identifier.bibliographicCitation | Journal of Nutrition and Health, v.46, no.6, pp.521 - 530 | - |
dc.relation.isPartOf | Journal of Nutrition and Health | - |
dc.citation.title | Journal of Nutrition and Health | - |
dc.citation.volume | 46 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 521 | - |
dc.citation.endPage | 530 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001836668 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Hemodialysis patients | - |
dc.subject.keywordAuthor | Hs-CRP | - |
dc.subject.keywordAuthor | MIA syndrome | - |
dc.subject.keywordAuthor | Protein intake | - |
dc.subject.keywordAuthor | Serum albumin | - |
dc.identifier.url | https://e-jnh.org/DOIx.php?id=10.4163/jnh.2013.46.6.521 | - |
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