The Utility of Magnetic Resonance Imaging in Inflammatory Myopathy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진주 | - |
dc.contributor.author | 이승훈 | - |
dc.contributor.author | 백승삼 | - |
dc.contributor.author | 유대현 | - |
dc.date.accessioned | 2022-07-16T07:52:25Z | - |
dc.date.available | 2022-07-16T07:52:25Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2013-10 | - |
dc.identifier.issn | 2093-940X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161743 | - |
dc.description.abstract | Objective. The idiopathic inflammatory myopathies (IIMs) are chronic systemic connective tissue diseases. The muscle biopsy is a definitive diagnostic tool but blind biopsy sometimes produces to negative results. Magnetic resonance imaging (MRI) as a tool for early diagnosis, guidance for biopsy, assessing extent of lesions and monitoring therapy in IIMs has been reported. The aim of this study is to assess the association of thigh inflammation through MRI and biopsy specimens with clinical findings. Methods. Sixty patients diagnosed with dermatomyositis (DM) or polymyositis (PM) from 2004 to 2011 in one center of rheumatology were enrolled. We reviewed clinical, laboratory, histopathologic and MRI of thigh data at initial diagnosis. The inflammation grades by MRI and histopathology of muscles were evaluated through 4-point scoring systems. Results. The laboratory findings for aldolase and CK differed significantly between DM patients (68.3%) and PM patients (31.7%). Fasciitis was detected by MRI in 43.3% of patients, of whom 88.5% had DM (p<0.05). The fasciitis was also associated with myalgia (p<0.05). Almost all MRI findings were symmetric except for two patients. The mean of total signal intensity was higher in patients with decreased muscle power. The signal intensity of affected muscle was slightly associated with muscle enzymes and histopathologic grading. Conclusion. Fasciitis was observed more in DM patients. MRI findings were associated with muscle enzymes and histopathologic grading. Signal intensity on MRI may be useful for measurement of disease activity in acute IIMs. The noninvasive nature and high sensitivity of muscle inflammation suggest that MRI images should be considered prior to muscle biopsy and treatment of IIMs. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 대한류마티스학회 | - |
dc.title | The Utility of Magnetic Resonance Imaging in Inflammatory Myopathy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 이승훈 | - |
dc.contributor.affiliatedAuthor | 백승삼 | - |
dc.contributor.affiliatedAuthor | 유대현 | - |
dc.identifier.doi | 10.4078/jrd.2013.20.5.297 | - |
dc.identifier.bibliographicCitation | 대한류마티스학회지, v.20, no.5, pp.297 - 302 | - |
dc.relation.isPartOf | 대한류마티스학회지 | - |
dc.citation.title | 대한류마티스학회지 | - |
dc.citation.volume | 20 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 297 | - |
dc.citation.endPage | 302 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART001817324 | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Inflammatory myopathy | - |
dc.subject.keywordAuthor | MRI | - |
dc.identifier.url | https://kiss.kstudy.com/thesis/thesis-view.asp?key=3187664 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.