Carbohydrate but not fat is associated with elevated aminotransferases
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwon, O. W. | - |
dc.contributor.author | Jun, D. W. | - |
dc.contributor.author | Lee, S. M. | - |
dc.contributor.author | Lee, K. N. | - |
dc.contributor.author | Lee, H. L. | - |
dc.contributor.author | Lee, O. Y. | - |
dc.contributor.author | Yoon, B. C. | - |
dc.contributor.author | Choi, H. S. | - |
dc.date.accessioned | 2022-07-16T15:31:13Z | - |
dc.date.available | 2022-07-16T15:31:13Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2012-05 | - |
dc.identifier.issn | 0269-2813 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/165688 | - |
dc.description.abstract | Background Recently, many studies reported that high carbohydrate and simple sugar intake increase a risk of obesity and metabolic syndrome significantly. Aim To investigate the effect of carbohydrate on aminotransferase levels in Korea, where the proportion of carbohydrate in meals is extremely high but fat is low. Methods We used the data of Korean National Health and Nutrition Examination Surveys (KNHANES). A total of 19 749 people were included. Amounts and types of consumed foods were examined by the 24 h recall method. Results Mean carbohydrate and fat proportions in total energy intake were 67.7% and 17.4%, respectively. Aminotransferase activity increased according to the rise of the proportion of carbohydrate in the energy intake. A high carbohydrate intake (>70% of energy) was associated with abnormal aminotransferase activity and metabolic syndrome. After adjusting for covariates, such as age, energy intake and body mass index, abnormal aminotransferase activity was significantly associated with carbohydrate proportion. There was a negative correlation between fat proportion in the total energy intake and aminotransferase activity (P < 0.01). The relation between aminotransferase activity and carbohydrate composition showed a J-shaped curve. The lowest point (the J point) was located at 50-60% carbohydrate. Conclusions The proportion of carbohydrate in energy intake but not fat is positively correlated with abnormal aminotransferase activity in Koreans. This finding may be useful in planning a strategy of nutrition education for NAFLD in countries where the proportion of carbohydrate in most meals is extremely high. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Carbohydrate but not fat is associated with elevated aminotransferases | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jun, D. W. | - |
dc.contributor.affiliatedAuthor | Lee, H. L. | - |
dc.contributor.affiliatedAuthor | Lee, O. Y. | - |
dc.contributor.affiliatedAuthor | Yoon, B. C. | - |
dc.contributor.affiliatedAuthor | Choi, H. S. | - |
dc.identifier.doi | 10.1111/j.1365-2036.2012.05061.x | - |
dc.identifier.scopusid | 2-s2.0-84875693226 | - |
dc.identifier.wosid | 000302898400009 | - |
dc.identifier.bibliographicCitation | ALIMENTARY PHARMACOLOGY & THERAPEUTICS, v.35, no.9, pp.1064 - 1072 | - |
dc.relation.isPartOf | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | - |
dc.citation.title | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | - |
dc.citation.volume | 35 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1064 | - |
dc.citation.endPage | 1072 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | LIVER-DISEASE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | HEPATIC STEATOSIS | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | WEIGHT-LOSS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | DIETS | - |
dc.subject.keywordPlus | CONSUMPTION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2012.05061.x | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.