Sensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry
DC Field | Value | Language |
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dc.contributor.author | Ahn, Jang-Hyuk | - |
dc.contributor.author | Jeong, Young-Su | - |
dc.contributor.author | Lee, Tae Geol | - |
dc.contributor.author | Kim, Young-Pil | - |
dc.contributor.author | Kim, Hak-Sung | - |
dc.date.accessioned | 2022-07-16T16:23:29Z | - |
dc.date.available | 2022-07-16T16:23:29Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 1976-0280 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/166164 | - |
dc.description.abstract | A rapid and reliable analysis of toxins is prerequisite for food control and human healthcare. Here we demonstrate a simple and multiplexed assay of aflatoxins using time-of-flight secondary ion mass spectrometry (TOF-SIMS). By simply adsorbing either a single analyte or mixed ones onto a gold substrate, the corresponding secondary molecular ions ([M+H](+)) were clearly observed in a single mass spectrum. As a result of concentration-dependent peak intensity, quantitative and multiplexed analysis of different aflatoxin analogs from corns was accomplished with immunoaffinity column and TOF-SIMS analysis, which showed a good correlation with HPLC data. The detection sensitivity was estimated to be as low as 10 ng mL(-1) This approach presented here will find a wide application to detection of low-levels of toxins in a rapid and multiplexed way. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN BIOCHIP SOCIETY-KBCS | - |
dc.title | Sensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Young-Pil | - |
dc.identifier.doi | 10.1007/s13206-012-6105-8 | - |
dc.identifier.scopusid | 2-s2.0-84863340678 | - |
dc.identifier.wosid | 000301684500005 | - |
dc.identifier.bibliographicCitation | BIOCHIP JOURNAL, v.6, no.1, pp.34 - 40 | - |
dc.relation.isPartOf | BIOCHIP JOURNAL | - |
dc.citation.title | BIOCHIP JOURNAL | - |
dc.citation.volume | 6 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 34 | - |
dc.citation.endPage | 40 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001642705 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.subject.keywordPlus | SELF-ASSEMBLED MONOLAYERS | - |
dc.subject.keywordPlus | TOF-SIMS | - |
dc.subject.keywordPlus | QUANTITATIVE-ANALYSIS | - |
dc.subject.keywordPlus | SURFACE-ANALYSIS | - |
dc.subject.keywordPlus | B-1 | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | COLUMN | - |
dc.subject.keywordPlus | ELISA | - |
dc.subject.keywordPlus | HPLC | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordAuthor | Aflatoxin | - |
dc.subject.keywordAuthor | TOF-SIMS | - |
dc.subject.keywordAuthor | Quantification | - |
dc.subject.keywordAuthor | Multiplexed analysis | - |
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