Micropatterning Polydiacetylene Supramolecular Vesicles on Glass Substrates using a Pre-Patterned Hydrophobic Thin Film

Abstract

A micropatterning method for depositing polydiacetylene (PDA) supramolecular vesicles on glass substrates, employing a pre-patterned hydrophobic thin film, is presented. The pre-patterned hydrophobic thin film is used to define surface-exposed regions on hydrophilic glass substrates where selective immobilization of PDA vesicles takes place. The observation that fluorescent patterns are generated by heat treathttp://dx.doi.org/10.1002/macp.201100678ment of the deposited PDAs demonstrates that the vesicles are successfully immobilized in the form of micropatterns. Finally, the possibility that this strategy may be used to design a vesicle-based sensor chip system is demonstrated by the observation that fluorescence patterns are generated when the immobilized PDA vesicles interact with cyclodextrin.