Control of adhesion, focal adhesion assembly, and differentiation of myoblasts by enzymatically crosslinked cell-interactive hydrogels
DC Field | Value | Language |
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dc.contributor.author | Jun, Indong | - |
dc.contributor.author | Park, Kyung Min | - |
dc.contributor.author | Lee, Dong Yun | - |
dc.contributor.author | Park, Ki Dong | - |
dc.contributor.author | Shin, Heungsoo | - |
dc.date.accessioned | 2022-07-16T19:08:22Z | - |
dc.date.available | 2022-07-16T19:08:22Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2011-09 | - |
dc.identifier.issn | 1598-5032 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/167655 | - |
dc.description.abstract | The development of an artificial matrix is critical as both a substrate to control the cell behavior and as a tool for examining the roles of cellular microenvironment in biology. This study developed cell-interactive hydrogels containing a Arg-Gly-Asp (RGD) peptide, cross-linked via bio-inspired enzymatic processes using H2O2 and horseradish peroxidase (HRP) as the initiators and examined how they controlled myoblast functions. The cell-interactive hydrogels modulated the adhesion and proliferation of myoblast, depending on the peptide density. Furthermore, the expression of focal adhesion proteins and myogenic differentiation were up-regulated significantly in myoblasts cultured on peptide-incorporated hydrogels. Therefore, the novel hydrogel system can be used to regulate the cell function for many tissue engineering applications. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | POLYMER SOC KOREA | - |
dc.title | Control of adhesion, focal adhesion assembly, and differentiation of myoblasts by enzymatically crosslinked cell-interactive hydrogels | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Dong Yun | - |
dc.identifier.doi | 10.1007/s13233-011-0909-6 | - |
dc.identifier.scopusid | 2-s2.0-80052672896 | - |
dc.identifier.wosid | 000293963700007 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR RESEARCH, v.19, no.9, pp.911 - 920 | - |
dc.relation.isPartOf | MACROMOLECULAR RESEARCH | - |
dc.citation.title | MACROMOLECULAR RESEARCH | - |
dc.citation.volume | 19 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 911 | - |
dc.citation.endPage | 920 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001576168 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | MESENCHYMAL STEM-CELLS | - |
dc.subject.keywordPlus | MATRIX ELASTICITY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | MICROENVIRONMENTS | - |
dc.subject.keywordPlus | PROLIFERATION | - |
dc.subject.keywordPlus | MORPHOGENESIS | - |
dc.subject.keywordPlus | STIMULATION | - |
dc.subject.keywordPlus | ATTACHMENT | - |
dc.subject.keywordPlus | MYOGENESIS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordAuthor | in situ gelatin | - |
dc.subject.keywordAuthor | enzyme polyerization | - |
dc.subject.keywordAuthor | RGD peptide | - |
dc.subject.keywordAuthor | myoblast adhesion | - |
dc.subject.keywordAuthor | myogenic differentiation | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs13233-011-0909-6 | - |
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