Controllable in-situ hydrogels membrane formation using microfluidics
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Eunpyo | - |
dc.contributor.author | Jun, Indong | - |
dc.contributor.author | Park, Kyung Min | - |
dc.contributor.author | Park, Ki Dong | - |
dc.contributor.author | Shin, Heungsoo | - |
dc.contributor.author | Park, Jungyul | - |
dc.date.accessioned | 2022-07-16T19:17:18Z | - |
dc.date.available | 2022-07-16T19:17:18Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2011-09 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/167719 | - |
dc.description.abstract | This paper reports a novel method for the in-situ hydrogel membrane fabrication in a simple PDMS channel. We used two separate solutions of 0.0625 wt% of H2O2 in PBS with the 5.2 wt% of the Tetronic-succinic anhydride-tyramine (Tet-SA-TA), and 0.0625 mg/ml of horseradish peroxidase (HRP) in PBS with the same concentration of Tet-SA-TA. These two solutions were introduced into the typical microfluidic channel and the mixing of these solutions spontaneously formed the in-situ crosslinked hydrogels membrane in the microfluidic channel. The width of the membrane can be controlled quantitatively by adjusting gelation time and the velocity of microfluidics. Moreover, by using the formed inner-channel membrane, the permeation of chemical molecules through the membrane was observed and its quantitative value was analyzed with multiphysics modeling. The parallel hydrogel membranes were also formed using a time-dependent procedure, and, in addition, this separated channel by the hydrogel membranes was applied for the generation of stable concentration gradients into the microchannel. These results can be used to realize the complicated diffusive 3D structure, such as biomimetic blood vessels. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | IEEE | - |
dc.title | Controllable in-situ hydrogels membrane formation using microfluidics | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Heungsoo | - |
dc.identifier.doi | 10.1109/NEMS.2011.6017387 | - |
dc.identifier.scopusid | 2-s2.0-80053305908 | - |
dc.identifier.bibliographicCitation | NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, pp.441 - 444 | - |
dc.relation.isPartOf | NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems | - |
dc.citation.title | NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems | - |
dc.citation.startPage | 441 | - |
dc.citation.endPage | 444 | - |
dc.type.rims | ART | - |
dc.type.docType | Conference Paper | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | 3D Structure | - |
dc.subject.keywordPlus | Biomimetic blood vessels | - |
dc.subject.keywordPlus | Chemical molecules | - |
dc.subject.keywordPlus | Concentration gradients | - |
dc.subject.keywordPlus | Cross-linked hydrogels | - |
dc.subject.keywordPlus | Gelation time | - |
dc.subject.keywordPlus | Horseradish peroxidase | - |
dc.subject.keywordPlus | Hydrogel membrane | - |
dc.subject.keywordPlus | In-situ | - |
dc.subject.keywordPlus | In-situ formations | - |
dc.subject.keywordPlus | Membrane formation | - |
dc.subject.keywordPlus | Microfluidic channel | - |
dc.subject.keywordPlus | Multi-physics modeling | - |
dc.subject.keywordPlus | Quantitative values | - |
dc.subject.keywordPlus | Separated channels | - |
dc.subject.keywordPlus | Time-dependent | - |
dc.subject.keywordPlus | Biomimetics | - |
dc.subject.keywordPlus | Blood vessels | - |
dc.subject.keywordPlus | Chemical analysis | - |
dc.subject.keywordPlus | Coagulation | - |
dc.subject.keywordPlus | Crosslinking | - |
dc.subject.keywordPlus | Fluidic devices | - |
dc.subject.keywordPlus | Gelation | - |
dc.subject.keywordPlus | Hydrophobicity | - |
dc.subject.keywordPlus | Membranes | - |
dc.subject.keywordPlus | Microchannels | - |
dc.subject.keywordPlus | Microfluidics | - |
dc.subject.keywordPlus | Separation | - |
dc.subject.keywordPlus | Hydrogels | - |
dc.subject.keywordAuthor | Concentration gradients | - |
dc.subject.keywordAuthor | Hydrogel membrane | - |
dc.subject.keywordAuthor | In-situ formation | - |
dc.subject.keywordAuthor | Microfluidics | - |
dc.identifier.url | https://ieeexplore.ieee.org/document/6017387 | - |
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