XRCC1 Polymorphisms and Risk of Papillary Thyroid Carcinoma in a Korean Sample
DC Field | Value | Language |
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dc.contributor.author | Ryu, Ri A. | - |
dc.contributor.author | Tae, Kyung | - |
dc.contributor.author | Min, Hyun Jung | - |
dc.contributor.author | Jeong, Jin Hyeok | - |
dc.contributor.author | Cho, Seok Hyun | - |
dc.contributor.author | Lee, Seung Hwan | - |
dc.contributor.author | Ahn, You Hern | - |
dc.date.accessioned | 2022-07-16T19:43:25Z | - |
dc.date.available | 2022-07-16T19:43:25Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2011-08 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/167910 | - |
dc.description.abstract | Polymorphisms of DNA repair genes, X-ray repair cross-complementing group 1 (XRCC1) might contribute to individual susceptibility to different types of cancers. We analyzed the relationship between XRCC1 polymorphisms and the risk of papillary thyroid carcinoma in a Korean sample. A hospital-based case-control study was performed in 111 papillary thyroid carcinoma patients and 100 normal control subjects. XRCC1 Arg194Trp and Arg399Gln single nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The XRCC1 Arg194Trp Arg/Trp genotype was significantly associated with a decreased risk of papillary thyroid carcinoma compared to that of Arg/Arg genotype (odds ratio [95% confidence intervals]; 0.550 [0.308-0.9831). There was no significant association between XRCC1 Arg399Gln genotypes and risk of papillary thyroid carcinoma. Based on these results, the XRCC1 Arg194Trp Arg/Trp genotype could be used as a useful molecular biomarker to predict genetic susceptibility for papillary thyroid carcinoma in Koreans. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | XRCC1 Polymorphisms and Risk of Papillary Thyroid Carcinoma in a Korean Sample | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Tae, Kyung | - |
dc.contributor.affiliatedAuthor | Jeong, Jin Hyeok | - |
dc.contributor.affiliatedAuthor | Cho, Seok Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hwan | - |
dc.identifier.doi | 10.3346/jkms.2011.26.8.991 | - |
dc.identifier.scopusid | 2-s2.0-80052683688 | - |
dc.identifier.wosid | 000293660200004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.26, no.8, pp.991 - 995 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 26 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 991 | - |
dc.citation.endPage | 995 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001575069 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | SQUAMOUS-CELL CARCINOMA | - |
dc.subject.keywordPlus | BASE EXCISION-REPAIR | - |
dc.subject.keywordPlus | DNA-REPAIR | - |
dc.subject.keywordPlus | NECK-CANCER | - |
dc.subject.keywordPlus | CHINESE POPULATION | - |
dc.subject.keywordPlus | GENE XRCC1 | - |
dc.subject.keywordPlus | HEAD | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | SENSITIVITY | - |
dc.subject.keywordAuthor | Polymorphisms | - |
dc.subject.keywordAuthor | XRCC1 | - |
dc.subject.keywordAuthor | SNP | - |
dc.subject.keywordAuthor | Papillary Thyroid Carcinoma | - |
dc.subject.keywordAuthor | Susceptibility | - |
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