Cortical Thinning in Verbal, Visual, and Both Memory-predominant Mild Cognitive Impairment
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Min-Jeong | - |
dc.contributor.author | Im, Kiho | - |
dc.contributor.author | Lee, Jong-Min | - |
dc.contributor.author | Park, Aram | - |
dc.contributor.author | Chin, Juhee | - |
dc.contributor.author | Kim, Geon Ha | - |
dc.contributor.author | Kim, Jong Hun | - |
dc.contributor.author | Roh, Jee Hoon | - |
dc.contributor.author | Seo, Sang Won | - |
dc.contributor.author | Na, Duk L. | - |
dc.date.accessioned | 2022-07-16T19:56:58Z | - |
dc.date.available | 2022-07-16T19:56:58Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2011-07 | - |
dc.identifier.issn | 0893-0341 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168061 | - |
dc.description.abstract | The amnestic form of mild cognitive impairment (aMCI) is likely a precursor of Alzheimer disease (AD). Both verbal and visual memory tests are used in the diagnosis of aMCI; however, it is unknown which type of test is superior at predicting the underlying pathologic changes associated with AD. In this study, we compared the topography of cortical thinning among 3 subtypes of patients with aMCI: 33 patients with predominant verbal memory impairment (verbal-aMCI), 35 with predominant visual memory impairment (visual-aMCI), and 56 with both verbal and visual memory-predominant impairment (both-aMCI), and 143 patients with normal cognition. As a result, patients with verbal-aMCI showed cortical thinning in the left anterior and medial temporal regions compared with individuals with normal cognition, while those with visual-aMCI did not show significant cortical thinning. The cortical thinning areas of both-aMCI group overlapped those of verbal-aMCI but were more widespread involving the bilateral temporal regions. These findings suggest that the verbal-aMCI and both-aMCI are more likely to be a precursor of AD than visual-aMCI, and that both-aMCI may be more advanced subtype than verbal-aMCI on the spectrum from MCI to AD. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Cortical Thinning in Verbal, Visual, and Both Memory-predominant Mild Cognitive Impairment | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Jong-Min | - |
dc.identifier.doi | 10.1097/WAD.0b013e3182076d31 | - |
dc.identifier.scopusid | 2-s2.0-80052220134 | - |
dc.identifier.wosid | 000294206600009 | - |
dc.identifier.bibliographicCitation | Alzheimer Disease & Associated Disorders, v.25, no.3, pp.242 - 249 | - |
dc.relation.isPartOf | Alzheimer Disease & Associated Disorders | - |
dc.citation.title | Alzheimer Disease & Associated Disorders | - |
dc.citation.volume | 25 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 242 | - |
dc.citation.endPage | 249 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Pathology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Pathology | - |
dc.subject.keywordPlus | GRAY-MATTER LOSS | - |
dc.subject.keywordPlus | ALZHEIMERS-DISEASE | - |
dc.subject.keywordPlus | LEWY BODIES | - |
dc.subject.keywordPlus | THICKNESS | - |
dc.subject.keywordPlus | BRAIN | - |
dc.subject.keywordPlus | DEMENTIA | - |
dc.subject.keywordPlus | VOLUME | - |
dc.subject.keywordPlus | REGISTRATION | - |
dc.subject.keywordPlus | CONVERSION | - |
dc.subject.keywordPlus | TESTS | - |
dc.subject.keywordAuthor | amnestic mild cognitive impairment | - |
dc.subject.keywordAuthor | verbal memory | - |
dc.subject.keywordAuthor | visual memory | - |
dc.subject.keywordAuthor | cortical thickness | - |
dc.subject.keywordAuthor | magnetic resonance imaging | - |
dc.subject.keywordAuthor | Alzheimer disease | - |
dc.identifier.url | https://journals.lww.com/alzheimerjournal/Fulltext/2011/07000/Cortical_Thinning_in_Verbal,_Visual,_and_Both.9.aspx | - |
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