Expression of activated HER2 in human testes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Inchoel | - |
dc.contributor.author | Kim, Hyun Joo | - |
dc.contributor.author | Nah, Won Heum | - |
dc.contributor.author | Park, Hyun Jun | - |
dc.contributor.author | Gye, Myung Chan | - |
dc.contributor.author | Park, Hae Young | - |
dc.date.accessioned | 2022-07-16T20:27:35Z | - |
dc.date.available | 2022-07-16T20:27:35Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2011-06 | - |
dc.identifier.issn | 0015-0282 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168304 | - |
dc.description.abstract | The her2 messenger RNA (mRNA) was the most abundant among the erb type-1 tyrosine kinase receptors mRNA in human testis and was statistically significantly decreased in impaired spermatogenesis. Testicular HER2 was tyrosine phosphorylated and strongly expressed in spermatogonia, early spermatocytes, elongating/elongated spermatids, Sertoli cells, Leydig cells, and peritubular cells, suggesting that activated HER2 participates in mitosis and meiotic entry of germ cells, spermiogenesis, and steroidogenesis via mediating the epidermal growth factor-growth factor signaling. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Expression of activated HER2 in human testes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Inchoel | - |
dc.contributor.affiliatedAuthor | Gye, Myung Chan | - |
dc.identifier.doi | 10.1016/j.fertnstert.2011.04.043 | - |
dc.identifier.scopusid | 2-s2.0-79959693884 | - |
dc.identifier.wosid | 000292034100109 | - |
dc.identifier.bibliographicCitation | FERTILITY AND STERILITY, v.95, no.8, pp.2725 - 2728 | - |
dc.relation.isPartOf | FERTILITY AND STERILITY | - |
dc.citation.title | FERTILITY AND STERILITY | - |
dc.citation.volume | 95 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 2725 | - |
dc.citation.endPage | 2728 | - |
dc.type.rims | ART | - |
dc.type.docType | Editorial Material | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalResearchArea | Reproductive Biology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Reproductive Biology | - |
dc.subject.keywordPlus | EPIDERMAL-GROWTH-FACTOR | - |
dc.subject.keywordPlus | BREAST-CANCER | - |
dc.subject.keywordPlus | LEYDIG-CELLS | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordPlus | LOCALIZATION | - |
dc.subject.keywordPlus | NETWORK | - |
dc.subject.keywordPlus | ERBB-2 | - |
dc.subject.keywordAuthor | Germ cells | - |
dc.subject.keywordAuthor | HER2 | - |
dc.subject.keywordAuthor | human | - |
dc.subject.keywordAuthor | soma | - |
dc.subject.keywordAuthor | testis | - |
dc.subject.keywordAuthor | tyrosine phosphorylated | - |
dc.identifier.url | https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S001502821100656X?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS001502821100656X%3Fshowall%3Dtrue&referrer= | - |
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