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The Effect of Conjugating RGD into 3D Alginate Hydrogels on Adipogenic Differentiation of Human Adipose-Derived Stromal Cells

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dc.contributor.authorKang, Sun-Woong-
dc.contributor.authorCha, Byung-Hyun-
dc.contributor.authorPark, Honghyun-
dc.contributor.authorPark, Kwang-Sook-
dc.contributor.authorLee, Kuen Yong-
dc.contributor.authorLee, Soo-Hong-
dc.date.accessioned2022-07-16T20:50:35Z-
dc.date.available2022-07-16T20:50:35Z-
dc.date.issued2011-05-
dc.identifier.issn1616-5187-
dc.identifier.issn1616-5195-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168571-
dc.description.abstractThe effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin alpha 1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels significantly enhanced the adipogenic differentiation of human ASCs to exhibit higher expression levels of oil red O staining and adipogenic genes compared to those of the control group (unmodified gels). These results suggest potential applications of RGD-modified alginate gels for adipose tissue regeneration.-
dc.format.extent7-
dc.language영어-
dc.language.isoENG-
dc.publisherJohn Wiley & Sons Ltd.-
dc.titleThe Effect of Conjugating RGD into 3D Alginate Hydrogels on Adipogenic Differentiation of Human Adipose-Derived Stromal Cells-
dc.typeArticle-
dc.publisher.location독일-
dc.identifier.doi10.1002/mabi.201000479-
dc.identifier.scopusid2-s2.0-79955717786-
dc.identifier.wosid000290443200011-
dc.identifier.bibliographicCitationMacromolecular Bioscience, v.11, no.5, pp 673 - 679-
dc.citation.titleMacromolecular Bioscience-
dc.citation.volume11-
dc.citation.number5-
dc.citation.startPage673-
dc.citation.endPage679-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalResearchAreaPolymer Science-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Biomaterials-
dc.relation.journalWebOfScienceCategoryPolymer Science-
dc.subject.keywordPlusADHESION-
dc.subject.keywordPlusPEPTIDE-
dc.subject.keywordPlusINTEGRINS-
dc.subject.keywordPlusCULTURE-
dc.subject.keywordAuthoradhesion-
dc.subject.keywordAuthorbiological applications of polymers-
dc.subject.keywordAuthorbiomaterials-
dc.subject.keywordAuthorhydrogels-
dc.subject.keywordAuthortissue engineering-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1002/mabi.201000479-
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