Identification of Antigenic Proteins in Trichomonas vaginalis
DC Field | Value | Language |
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dc.contributor.author | Lee, Hye-Yeon | - |
dc.contributor.author | Hyung, Sujin | - |
dc.contributor.author | Lee, Jong Woong | - |
dc.contributor.author | Kim, Juri | - |
dc.contributor.author | Shin, Myeong Heon | - |
dc.contributor.author | Ryu, Jae-Sook | - |
dc.contributor.author | Park, Soon-Jung | - |
dc.date.accessioned | 2022-07-16T21:29:22Z | - |
dc.date.available | 2022-07-16T21:29:22Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2011-03 | - |
dc.identifier.issn | 0023-4001 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/168885 | - |
dc.description.abstract | Trichomoniasis is a sexually transmitted disease due to infection with Trichomonas vaginalis, and it can cause serious consequences for women's health. To study the virulence factors of this pathogen, T vaginalis surface proteins were investigated using polyclonal antibodies specific to the membrane fractions of T vaginalis. The T vaginalis expression library was constructed by cloning the cDNA derived from mRNA of T vaginalis into a phage lambda Uni-ZAP XR vector, and then used for immunoscreening with the anti-membrane proteins of T. vaginalis antibodies. The immunoreactive proteins identified included adhesion protein AP65-1, alpha-actinin, kinesin-associated protein, teneurin, and 2 independent hypothetical proteins. Immunofluorescence assays showed that AP65-1, one of the identified immunogenic clones, is prevalent in the whole body of T vaginalis. This study led us to identify T vaginalis proteins which may stimulate immune responses by human cells. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC PARASITOLOGY, SEOUL NATL UNIV COLL MEDI | - |
dc.title | Identification of Antigenic Proteins in Trichomonas vaginalis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryu, Jae-Sook | - |
dc.identifier.doi | 10.3347/kjp.2011.49.1.79 | - |
dc.identifier.scopusid | 2-s2.0-79953288488 | - |
dc.identifier.wosid | 000289540600013 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF PARASITOLOGY, v.49, no.1, pp.79 - 83 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF PARASITOLOGY | - |
dc.citation.title | KOREAN JOURNAL OF PARASITOLOGY | - |
dc.citation.volume | 49 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 79 | - |
dc.citation.endPage | 83 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001544518 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Parasitology | - |
dc.relation.journalWebOfScienceCategory | Parasitology | - |
dc.subject.keywordPlus | MOLECULAR CHARACTERIZATION | - |
dc.subject.keywordPlus | IRON | - |
dc.subject.keywordPlus | ADHESINS | - |
dc.subject.keywordPlus | CYTOADHERENCE | - |
dc.subject.keywordPlus | SURFACE | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | CLONING | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | AP65 | - |
dc.subject.keywordAuthor | Trichomonas vaginalis | - |
dc.subject.keywordAuthor | antigenic protein | - |
dc.subject.keywordAuthor | membrane protein | - |
dc.subject.keywordAuthor | immunoscreening | - |
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