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Effect of Amination on the biological activity of beta-glucan from Sangwhang (Phellinus linteus)

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dc.contributor.authorBae, In Young-
dc.contributor.authorShin, Ji-Yoon-
dc.contributor.authorLee, Hyeon Gyu-
dc.date.accessioned2022-10-07T10:19:32Z-
dc.date.available2022-10-07T10:19:32Z-
dc.date.created2022-08-26-
dc.date.issued2008-06-
dc.identifier.issn1226-7708-
dc.identifier.urihttps://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/172017-
dc.description.abstractbeta-Glucans, which were isolated from sangwhang (Phellinus linteus), were subjected to reductive amination and the biological properties of the derivative were investigated. The degree of substitution of the aminated sangwhang beta-glucan was calculated by elemental analysis to be 1.13. Bronchoalveolar lavage (BAL) experiments showed that the aminated derivative increased nitric oxide production. In addition, the amination enhanced in vitro cytotoxic activities against HT1080 and SNU-C2A cell lines. Thus, the aminated derivative is shown to enhance immune systems by the incorporation of amino groups into the polyrner structure.-
dc.language영어-
dc.language.isoen-
dc.publisherKOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST-
dc.titleEffect of Amination on the biological activity of beta-glucan from Sangwhang (Phellinus linteus)-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Hyeon Gyu-
dc.identifier.scopusid2-s2.0-49649106999-
dc.identifier.wosid000257488700040-
dc.identifier.bibliographicCitationFOOD SCIENCE AND BIOTECHNOLOGY, v.17, no.3, pp.683 - 686-
dc.relation.isPartOfFOOD SCIENCE AND BIOTECHNOLOGY-
dc.citation.titleFOOD SCIENCE AND BIOTECHNOLOGY-
dc.citation.volume17-
dc.citation.number3-
dc.citation.startPage683-
dc.citation.endPage686-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.identifier.kciidART001264344-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaFood Science & Technology-
dc.relation.journalWebOfScienceCategoryFood Science & Technology-
dc.subject.keywordPlusMUSHROOM INONOTUS-OBLIQUUS-
dc.subject.keywordPlusPLEUROTUS-TUBER-REGIUM-
dc.subject.keywordPlusNITRIC-OXIDE-
dc.subject.keywordPlusPOLYSACCHARIDE-
dc.subject.keywordPlusMACROPHAGES-
dc.subject.keywordPlusRAT-
dc.subject.keywordPlus(1-&gt-
dc.subject.keywordPlus3)-BETA-D-GLUCANS-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusSCLEROTIUM-
dc.subject.keywordPlusMASS-
dc.subject.keywordAuthorsangwhang-
dc.subject.keywordAuthorbeta-glucan-
dc.subject.keywordAuthoramination-
dc.subject.keywordAuthornitric oxide-
dc.subject.keywordAuthorcytotoxic activity-
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