升麻葛根湯의 항히스타민 효과 및 IL-4와 GM-CSF 발현에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김홍배 | - |
dc.contributor.author | 김원일 | - |
dc.contributor.author | 이승연 | - |
dc.date.accessioned | 2022-10-07T11:58:02Z | - |
dc.date.available | 2022-10-07T11:58:02Z | - |
dc.date.created | 2022-09-19 | - |
dc.date.issued | 2006-04 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/172500 | - |
dc.description.abstract | Objectives : We investigated the effect of Sungmagalkuntang(SGT) on the allergy. Methods : We conformed compound 48/80-induced active systemic anaphylatic shock, anti- dinitrophenyl IgE-mediated passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock. Also observed IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3. Histamine release is measured in RBL-2H3. Results : SGT inhibited active systemic anaphylatic shock, passive cutaneous anaphylaxis and ovalbumin-induced anaphylatic shock by oral administration. We observed that SGT was concentration-dependently reduced IL-4 and GM-CSF mRNA expression in ovalbumin-induced allergic lung tissue and RBL-2H3 by SGT. In addition, SGT reduced histamine release in RBL-2H3. Conclusions : These results indicate that SGT has anti-histamic effect and controls IL-4 and GM-CSF mRNA expression on allergy. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한방소아과학회 | - |
dc.title | 升麻葛根湯의 항히스타민 효과 및 IL-4와 GM-CSF 발현에 미치는 영향 | - |
dc.title.alternative | Anti-histamic Effect and IL-4 and GM-CSF mRNA Expression on Sungmagalkuntang | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김홍배 | - |
dc.identifier.bibliographicCitation | 대한한방소아과학회지, v.20, no.1, pp.69 - 83 | - |
dc.relation.isPartOf | 대한한방소아과학회지 | - |
dc.citation.title | 대한한방소아과학회지 | - |
dc.citation.volume | 20 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 69 | - |
dc.citation.endPage | 83 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART001180917 | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | other | - |
dc.subject.keywordAuthor | Sungmagalkun-tang(SGT) | - |
dc.subject.keywordAuthor | Anti-histamic Effect | - |
dc.subject.keywordAuthor | IL-4 | - |
dc.subject.keywordAuthor | GM-CS | - |
dc.subject.keywordAuthor | Sungmagalkun-tang(SGT) | - |
dc.subject.keywordAuthor | Anti-histamic Effect | - |
dc.subject.keywordAuthor | IL-4 | - |
dc.subject.keywordAuthor | GM-CS | - |
dc.identifier.url | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001180917 | - |
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