Prevalence of advanced hepatic fibrosis and comorbidity in metabolic dysfunction-associated fatty liver disease in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, Mimi | - |
dc.contributor.author | Yoon, Eileen Laurel | - |
dc.contributor.author | Cho, Seon | - |
dc.contributor.author | Lee, Chul-min | - |
dc.contributor.author | Kang, Bo-Kyeong | - |
dc.contributor.author | Park, Huiyul | - |
dc.contributor.author | Jun, Dae Won | - |
dc.contributor.author | Nah, Eun-Hee | - |
dc.date.accessioned | 2022-12-20T10:36:54Z | - |
dc.date.available | 2022-12-20T10:36:54Z | - |
dc.date.created | 2022-05-04 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.issn | 1478-3223 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/173240 | - |
dc.description.abstract | Background & Aims There are several reports on the prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD). However, the prevalence of advanced hepatic fibrosis in MAFLD is largely unknown. We aimed to evaluate the prevalence of advanced fibrosis in MAFLD. Methods A total of 6775 subjects from nationwide 13 health check-up centres were included in this cross-sectional study. Fatty liver was evaluated using ultrasonography. Significant (≥F2) and advanced (≥F3) hepatic fibrosis were defined by MRE thresholds of 3.0 kPa (range: 2.99–3.65 kPa) and 3.6 kPa (range: 3.4–3.9 kPa) respectively. The sex- and age-standardized prevalence of MAFLD and hepatic fibrosis was estimated. Results The sex- and age-standardized prevalence of MAFLD was 33.9%. The prevalence of obesity (BMI ≥25 kg/m2) in MAFLD was 71.1%, and 79.0% of obese subjects had MAFLD. The prevalence of diabetes in MAFLD was 13.3%, and 73.6% of subjects with diabetes had MAFLD. The sex- and age-standardized prevalence of significant (≥F2) and advanced hepatic fibrosis (≥F3) amongst MAFLD was 9.7% (range: 3.0–9.8%) and 3.0% (range: 2.6–4.6%) respectively. The prevalence of advanced hepatic fibrosis in overweight/obese (group I), lean (group II) and diabetic (group III) MAFLD was 2.3%, 3.1% and 9.5% respectively. Conclusion The sex- and age-standardized prevalence of advanced fibrosis was 3.0% (range: 2.6–4.6%) in subjects with MAFLD. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Prevalence of advanced hepatic fibrosis and comorbidity in metabolic dysfunction-associated fatty liver disease in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Mimi | - |
dc.contributor.affiliatedAuthor | Yoon, Eileen Laurel | - |
dc.contributor.affiliatedAuthor | Kang, Bo-Kyeong | - |
dc.contributor.affiliatedAuthor | Jun, Dae Won | - |
dc.identifier.doi | 10.1111/liv.15259 | - |
dc.identifier.scopusid | 2-s2.0-85128193278 | - |
dc.identifier.wosid | 000780747300001 | - |
dc.identifier.bibliographicCitation | LIVER INTERNATIONAL, v.42, no.7, pp.1536 - 154 | - |
dc.relation.isPartOf | LIVER INTERNATIONAL | - |
dc.citation.title | LIVER INTERNATIONAL | - |
dc.citation.volume | 42 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1536 | - |
dc.citation.endPage | 154 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Early Access | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE ELASTOGRAPHY | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | NAFLD | - |
dc.subject.keywordPlus | STEATOSIS | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordAuthor | advanced fibrosis | - |
dc.subject.keywordAuthor | magnetic resonance imaging | - |
dc.subject.keywordAuthor | metabolic dysfunction-associated fatty liver disease | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/liv.15259 | - |
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