Clinical efficacy and tolerance of 1% nadifloxacin cream in the treatment of mild to moderate acne vulgaris in South Korea
DC Field | Value | Language |
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dc.contributor.author | Choi, Won Jun | - |
dc.contributor.author | Kim, Kwang Joong | - |
dc.contributor.author | Kim, Nack In | - |
dc.contributor.author | Kye, Young Chul | - |
dc.contributor.author | Suh, Dae Hun | - |
dc.contributor.author | Lee, Joo Heung | - |
dc.contributor.author | Kim, Myeung Nam | - |
dc.contributor.author | Lee, Eun So | - |
dc.contributor.author | Lee, Ju Hee | - |
dc.contributor.author | Ro, Young Suck | - |
dc.date.accessioned | 2022-12-20T16:09:06Z | - |
dc.date.available | 2022-12-20T16:09:06Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 0494-4739 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/174325 | - |
dc.description.abstract | Background: Antimicrobials have been a mainstay of inflammatory acne treatment for more than 30 years. However, antibiotic-resistant propionibacteria had been isolated with increased frequency, and associated with failure to respond to antibiotic therapy. Objective: The aim of this study was to investigate the clinical efficacy and tolerance of 1% nadifloxacin cream. Methods: In the final analysis, 197 patients with mild to moderate facial acne vulgaris were enrolled. The patients were instructed to apply 1% nadifloxacin cream twice daily to the affected skin after washing the face. Following 2 and 4 weeks of treatment, patients were observed for clinical response: number of the acne lesions, Korea acne grading system (KAGS), global improvement, and occurrence of adverse reactions. Results: During 4 weeks of treatment, nadifloxacin caused significant reduction in the number of inflamed papulo-pustular lesions and open/closed comedones. In addition, significant reduction of KAGS was observed. About 96% of patients showed clinical improvement in the overall evaluation of the therapeutic effect by physicians. All reported adverse events were mild. Conclusion: This study shows that 1% nadifloxacin cream can be an effective and safe treatment for mild to moderate acne vulgaris. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한피부과학회 | - |
dc.title | Clinical efficacy and tolerance of 1% nadifloxacin cream in the treatment of mild to moderate acne vulgaris in South Korea | - |
dc.title.alternative | 경증 및 중등도의 한국인 여드름 환자에서 1% Nadifloxacin 크림(Nadixa(R))의 유효성 및 안전성 평가 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ro, Young Suck | - |
dc.identifier.scopusid | 2-s2.0-79960902781 | - |
dc.identifier.bibliographicCitation | Korean Journal of Dermatology, v.48, no.8, pp.665 - 671 | - |
dc.relation.isPartOf | Korean Journal of Dermatology | - |
dc.citation.title | Korean Journal of Dermatology | - |
dc.citation.volume | 48 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 665 | - |
dc.citation.endPage | 671 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001476922 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | 1% nadifloxacin cream | - |
dc.subject.keywordAuthor | Acne | - |
dc.subject.keywordAuthor | Treatment | - |
dc.identifier.url | https://kiss.kstudy.com/thesis/thesis-view.asp?key=2863969 | - |
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