The Development of Genipin-Crosslinked Poly(caprolactone) (PCL)/Gelatin Nanofibers for Tissue Engineering Applications
DC Field | Value | Language |
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dc.contributor.author | Kim, Min Sup | - |
dc.contributor.author | Jun, Indong | - |
dc.contributor.author | Shin, Young Min | - |
dc.contributor.author | Jang, Wonhee | - |
dc.contributor.author | Kim, Sun I. | - |
dc.contributor.author | Shin, Heungsoo | - |
dc.date.accessioned | 2022-12-20T19:23:15Z | - |
dc.date.available | 2022-12-20T19:23:15Z | - |
dc.date.created | 2022-08-27 | - |
dc.date.issued | 2010-01 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/175600 | - |
dc.description.abstract | Composite nano-fibers of poly(caprolactone) (PCL) and gelatin crosslinked with genipin are prepared. The contact angles and mechanical properties of crosslinked PCL-gelatin nanofibers decrease as the gelatin content increases. The proliferation of myoblasts is higher in the crosslinked PCL-gelatin nanofibers than in the PCL nanofibers, and the formation of myotubes is only observed on the crosslinked PCL-gelatin nanofibers. The expression level of myogenin, myosin heavy chain, and troponin T genes is increased as the gelatin content is increased. The results suggest that PCL-gelatin nanofibers crosslinked with genipin can be used as a substrate to modulate proliferation and differentiation of myoblasts, presenting potential applications in muscle tissue engineering. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | The Development of Genipin-Crosslinked Poly(caprolactone) (PCL)/Gelatin Nanofibers for Tissue Engineering Applications | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Heungsoo | - |
dc.identifier.doi | 10.1002/mabi.200900168 | - |
dc.identifier.scopusid | 2-s2.0-75749144243 | - |
dc.identifier.wosid | 000274394700009 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR BIOSCIENCE, v.10, no.1, pp.91 - 100 | - |
dc.relation.isPartOf | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.title | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 100 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | HUMAN SKELETAL-MUSCLE | - |
dc.subject.keywordPlus | BIOLOGICAL TISSUE | - |
dc.subject.keywordPlus | LINKING REACTION | - |
dc.subject.keywordPlus | CELL THERAPY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | GELATIN | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | MYOBLASTS | - |
dc.subject.keywordAuthor | electrospinning | - |
dc.subject.keywordAuthor | gelatin | - |
dc.subject.keywordAuthor | polycaprolactone | - |
dc.subject.keywordAuthor | skeletal muscles | - |
dc.subject.keywordAuthor | tissue engineering | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/mabi.200900168 | - |
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