자가면역질환 환자에서 장기간 당질 코르티코이드 복용에 의해 유발된 골다공증성 다발성 압박 골절

Abstract

Reduced bone mineral density precedes the development of vertebral fractures in patients under long term glucocorticoid therapy. Osteoporosis is a frequent complication in steroiddependent patients, and the risk of developing vertebral fractures in these patients is much higher than involutional osteoporosis. We described a 54-year-old patient who presented with autoimmune hepatitis and had a 6-year history of steroid medication. The patient had multiple compression fractures (T10∼L5) without trauma, and was treated successfully with multi level vertebroplasty and an intravenous injection of bisphosphonate without complications.