Comparison of icodextrin and 2.5% glucose in potassium metabolism by acute K+ load via dialysate in continuous ambulatory peritoneal dialysis patients
DC Field | Value | Language |
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dc.contributor.author | Yi, Joo-Hark | - |
dc.contributor.author | Yun, Yeo-Wook | - |
dc.contributor.author | Han, Sang Woong | - |
dc.contributor.author | Kim, Ho-Jung | - |
dc.date.accessioned | 2022-12-20T21:51:17Z | - |
dc.date.available | 2022-12-20T21:51:17Z | - |
dc.date.created | 2022-09-16 | - |
dc.date.issued | 2009-06 | - |
dc.identifier.issn | 1738-5997 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/176645 | - |
dc.description.abstract | This study aimed to compare the increment in plasma potassium concentration ([K+]) as well as the role of internal K+ balance for its changes following acute K+ supplementation between conventional 2.5% glucose (GD) and non-glucose containing dialysate (icodextrin, ID) in continuous ambulatory peritoneal dialysis (CAPD) patients. A total of 9 stable CAPD patients (5 men and 4 women; age, 56±13 years; 7 type-2 diabetics and 2 non-diabetics) on daily 4 exchanges of 2 L of glucose dialysate underwent the 6-hr dwell on fasting in the morning with 2 L of 2.5% glucose mixed with 20 mEq/L of KCl, and then the same regimen was repeated with icodextrin after 1-wk interval. The degree of intraperitoneal absorption was comparable, 65±2% in GD and 68+2% in ID, respectively (p=NS). However, despite the similar plasma K+ levels at the baseline of both regimens, its increment was significantly less in GD than ID, which was accompanied by more marked increase in the calculated intracellular K+ redistribution (68±3% vs. 52±3%, p<0.05). The basal levels of insulin were similar between the GD and ID groups. However, the change, checked up after 2 hours' dwell, from the basal insulin levels was much lower on ID. ID with a lesser degree of transcelluar K+ shift by the decreased secretion of insulin is more effective than the conventional glucose solution for acute K+ repletion via dialysate during CAPD. Furthermore, these results suggested that the role of insulin for the internal K+ balance was intact even in type-2 diabetic patients on CAPD. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Electrolyte and Blood Pressure Research | - |
dc.title | Comparison of icodextrin and 2.5% glucose in potassium metabolism by acute K+ load via dialysate in continuous ambulatory peritoneal dialysis patients | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Han, Sang Woong | - |
dc.identifier.doi | 10.5049/EBP.2009.7.1.25 | - |
dc.identifier.scopusid | 2-s2.0-76549113314 | - |
dc.identifier.bibliographicCitation | Electrolyte and Blood Pressure, v.7, no.1, pp.25 - 30 | - |
dc.relation.isPartOf | Electrolyte and Blood Pressure | - |
dc.citation.title | Electrolyte and Blood Pressure | - |
dc.citation.volume | 7 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 25 | - |
dc.citation.endPage | 30 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001347797 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.subject.keywordPlus | glucose | - |
dc.subject.keywordPlus | icodextrin | - |
dc.subject.keywordPlus | insulin | - |
dc.subject.keywordPlus | potassium | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | chronic glomerulonephritis | - |
dc.subject.keywordPlus | clinical article | - |
dc.subject.keywordPlus | continuous ambulatory peritoneal dialysis | - |
dc.subject.keywordPlus | dialysate | - |
dc.subject.keywordPlus | diet restriction | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | hypokalemia | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | non insulin dependent diabetes mellitus | - |
dc.subject.keywordPlus | potassium balance | - |
dc.subject.keywordPlus | potassium blood level | - |
dc.subject.keywordPlus | potassium cell level | - |
dc.subject.keywordPlus | potassium metabolism | - |
dc.subject.keywordPlus | supplementation | - |
dc.subject.keywordAuthor | Continuous ambulatory | - |
dc.subject.keywordAuthor | Hypokalemia | - |
dc.subject.keywordAuthor | Icodextrin | - |
dc.subject.keywordAuthor | Peritoneal dialysis | - |
dc.subject.keywordAuthor | Potassium supplementation | - |
dc.identifier.url | https://enbpr.org/DOIx.php?id=10.5049/EBP.2009.7.1.25 | - |
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