혈장교환술과 면역억제제 치료로 호전된 항사구체기저막 항체질환 1예A Case of Anti-Glomerular Basement Membrane Disease Improved by Early Plasmapheresis and Immunosuppression Therapy
- Other Titles
- A Case of Anti-Glomerular Basement Membrane Disease Improved by Early Plasmapheresis and Immunosuppression Therapy
- Authors
- 김지현; 유선진; 박준성; 이창화; 김근호; 강종명; 임소덕; 이종호
- Issue Date
- May-2009
- Publisher
- 대한신장학회
- Keywords
- Anti-glomerular basement membrane disease; Corticosteroids; Plasmapheresis; Cyclophosphamide
- Citation
- Kidney Research and Clinical Practice, v.28, no.3, pp.243 - 247
- Indexed
- KCI
- Journal Title
- Kidney Research and Clinical Practice
- Volume
- 28
- Number
- 3
- Start Page
- 243
- End Page
- 247
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/176749
- ISSN
- 2211-9132
- Abstract
- Anti-glomerular basement membrane disease is a rare autoimmune disease characterized by rapidly progressive renal failure and/or pulmonary hemorrhage. The presence of severe crescentic glomerular inflammation with linear deposition of immunoglobulin G along the glomerular basement membrane is pathognomonic. Because renal function is rapidly and often irretrievably destroyed, many patients require hemodialysis all through their lifetime. We report a case of 33 year(s)-old man who was diagnosed as anti-glomerular basement membrane disease without pulmonary hemorrhage. The patient was treated with pulse methylprednisolone and plasmapheresis followed by oral corticosteroid and cyclophosphamide. His renal function was successfully recovered with early diagnosis and aggressive treatment.
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