pH-Dependent Structures of an i-Motif DNA in Solution
DC Field | Value | Language |
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dc.contributor.author | Jin, Kyeong Sik | - |
dc.contributor.author | Shin, Su Ryon | - |
dc.contributor.author | Ahn, Byungcheol | - |
dc.contributor.author | Rho, Yecheol | - |
dc.contributor.author | Kim, Seon Jeong | - |
dc.contributor.author | Ree, Moonhor | - |
dc.date.accessioned | 2022-12-20T23:40:00Z | - |
dc.date.available | 2022-12-20T23:40:00Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2009-02 | - |
dc.identifier.issn | 1520-6106 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/177333 | - |
dc.description.abstract | We have investigated for the first time the structure of i-motif DNA in solution at various pH conditions by using synchrotron small-angle X-ray scattering technique. To facilitate direct structural. comparison between solution structures of i-motif DNA at various pH values, we created atomic coordinates of i-motif DNA from a fully folded to unfolded atomic model. Under mild acidic conditions, the conformations for i-motif DNA appeared to be similar to that of the partially unfolded i-motif atomic model in overall shape, rather than the fully folded i-motif atomic model. Collectively, our observations indicate that i-motif DNA molecule is structurally dynamic over a wide pH range, adopting multiple conformations ranging from the folded i-motif structure to a random coil conformation. As the i-motif structure has been used as an important component in nanomachines, we can therefore believe that the structural evidence presented herein will promote the development of future DNA-based molecular-actuator devices. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | pH-Dependent Structures of an i-Motif DNA in Solution | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Seon Jeong | - |
dc.identifier.doi | 10.1021/jp808186z | - |
dc.identifier.scopusid | 2-s2.0-65249147781 | - |
dc.identifier.wosid | 000263299400007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PHYSICAL CHEMISTRY B, v.113, no.7, pp.1852 - 1856 | - |
dc.relation.isPartOf | JOURNAL OF PHYSICAL CHEMISTRY B | - |
dc.citation.title | JOURNAL OF PHYSICAL CHEMISTRY B | - |
dc.citation.volume | 113 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1852 | - |
dc.citation.endPage | 1856 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.subject.keywordPlus | X-RAY-SCATTERING | - |
dc.subject.keywordPlus | ORGANOSILICATE DIELECTRIC FILMS | - |
dc.subject.keywordPlus | COPOLYMER THIN-FILMS | - |
dc.subject.keywordPlus | BIOLOGICAL MACROMOLECULES | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURE | - |
dc.subject.keywordPlus | ENERGY-TRANSFER | - |
dc.subject.keywordPlus | EVOLUTION | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | COMPLEXES | - |
dc.subject.keywordPlus | MACHINES | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/jp808186z | - |
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