Improvement of Differentiation and Mineralization of Pre-Osteoblasts on Composite Nanofibers of Poly(lactic acid) and Nanosized Bovine Bone Powder
DC Field | Value | Language |
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dc.contributor.author | Ko, Eun Kyoung | - |
dc.contributor.author | Jeong, Sung In | - |
dc.contributor.author | Lee, Ji Hye | - |
dc.contributor.author | Shin, Heungsoo | - |
dc.date.accessioned | 2022-12-21T00:17:22Z | - |
dc.date.available | 2022-12-21T00:17:22Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2008-12 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/177633 | - |
dc.description.abstract | The effect of NBM incorporation in PLA nanofibers on their mechanical properties and the differentiation and mineralization of osteoblasts was studied. At 20% NBM, the Young's modulus of the nanofibers was 37.78 +/- 4.23, significantly larger than that of pure PLA nanofibers. MCM-E1 pre-osteoblasts attached to both types of nanofibers and developed full osteogenic phenotypes. A profound effect of NBM on the mineralization of MCM-E1 pre-osteoblasts was confirmed, suggesting that NBM/PLA composite nanofibers exhibit properties similar to those of the native collagen-rich mineralized bone matrix, and could therefore serve as a temporary substrate for facilitating the differentiation and mineralization of bone-forming cells. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Improvement of Differentiation and Mineralization of Pre-Osteoblasts on Composite Nanofibers of Poly(lactic acid) and Nanosized Bovine Bone Powder | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Heungsoo | - |
dc.identifier.doi | 10.1002/mabi.200800089 | - |
dc.identifier.scopusid | 2-s2.0-60549100954 | - |
dc.identifier.wosid | 000262029100003 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR BIOSCIENCE, v.8, no.12, pp.1098 - 1107 | - |
dc.relation.isPartOf | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.title | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1098 | - |
dc.citation.endPage | 1107 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | COLLAGEN | - |
dc.subject.keywordAuthor | biodegradable | - |
dc.subject.keywordAuthor | composites | - |
dc.subject.keywordAuthor | fibers | - |
dc.subject.keywordAuthor | microstructure | - |
dc.subject.keywordAuthor | mineral | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/mabi.200800089 | - |
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