Comparison of efficacy of low-carbohydrate and low-fat diet education programs in non-alcoholic fatty liver disease: A randomized controlled study
DC Field | Value | Language |
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dc.contributor.author | Jang, Eun Chul | - |
dc.contributor.author | Jun, Dae Won | - |
dc.contributor.author | Lee, Seung Min | - |
dc.contributor.author | Cho, Yong kyun | - |
dc.contributor.author | Ahn, Sang Bong | - |
dc.date.accessioned | 2021-08-02T13:53:06Z | - |
dc.date.available | 2021-08-02T13:53:06Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1386-6346 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/17798 | - |
dc.description.abstract | Aim: Composition of macronutrients is important in non-alcoholic fatty liver disease (NAFLD). Diet education programs that mainly emphasize reducing fat consumption have been used for NAFLD patients. We compared the efficacy of conventional low-fat diet education with low-carbohydrate diet education in Korean NAFLD patients. Methods: One hundred and six NAFLD patients were randomly allocated to low-fat diet education or low-carbohydrate education groups for 8weeks. Liver chemistry, liver/spleen ratio, and visceral fat using abdominal tomography were measured. Results: Intrahepatic fat accumulation decreased significantly in the low-carbohydrate group compared to low-fat group (liver/spleen 0.85 vs. 0.92, P<0.05). Normalization of ALT activity at week 8 was 38.5% for the low-carbohydrate and 16.7% for the low-fat group (P=0.016). Not only liver enzyme, but also low density lipoprotein cholesterol and blood pressure levels significantly decreased in the low-carbohydrate group. Total energy intake was also further decreased in the low-carbohydrate group compared to the low-fat group. Although body weight changes were not different between the two groups, the carbohydrate group had a lower total abdominal fat amount. Conclusions: A low-carbohydrate diet program is more realistic and effective in reducing total energy intake and hepatic fat content in Korean NAFLD patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.title | Comparison of efficacy of low-carbohydrate and low-fat diet education programs in non-alcoholic fatty liver disease: A randomized controlled study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jun, Dae Won | - |
dc.identifier.doi | 10.1111/hepr.12918 | - |
dc.identifier.scopusid | 2-s2.0-85021726296 | - |
dc.identifier.wosid | 000424837000003 | - |
dc.identifier.bibliographicCitation | Hepatology Research, v.48, no.3, pp.E22 - E29 | - |
dc.relation.isPartOf | Hepatology Research | - |
dc.citation.title | Hepatology Research | - |
dc.citation.volume | 48 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | E22 | - |
dc.citation.endPage | E29 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordAuthor | carbohydrate | - |
dc.subject.keywordAuthor | fat | - |
dc.subject.keywordAuthor | non-alcoholic fatty liver disease | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/hepr.12918 | - |
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