Quantifying interactions between cell receptors and adhesion ligand-modified polymers in solution
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Kuen Yong | - |
dc.contributor.author | Kong, Hyun Joon | - |
dc.contributor.author | Mooney, David J. | - |
dc.date.accessioned | 2022-12-21T04:36:25Z | - |
dc.date.available | 2022-12-21T04:36:25Z | - |
dc.date.created | 2022-08-26 | - |
dc.date.issued | 2008-02 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/179026 | - |
dc.description.abstract | Specific interactions between cells and cell-interactive polymers in solution were investigated by the fluorescence resonance energy transfer (FRET) technique and rheological measurements. The green fluorescence emission was dramatically reduced when rhodamine-stained cells were mixed with a fluorescein-labeled RGD-alginate solution, compared with those mixed with no RGD-containing alginate solution, which indicated an occurrence of FRET and existence of specific interactions between the cells and the polymers in solution. Rheological measurements also confirmed the formation of ordered structures of cell/polymer mixtures, caused by specific cell-polymer interactions. The FRET method was able to provide a useful means of investigating cell-polymer interactions, both in a qualitative and quantitative manner, and this approach to monitoring and controlling specific interactions between cells and polymers could be useful in the design and tailoring of polymeric carriers for cells, as well as for biological drugs, especially for tissue engineering applications. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Quantifying interactions between cell receptors and adhesion ligand-modified polymers in solution | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Kuen Yong | - |
dc.identifier.doi | 10.1002/mabi.200700169 | - |
dc.identifier.scopusid | 2-s2.0-41249085855 | - |
dc.identifier.wosid | 000253741700002 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR BIOSCIENCE, v.8, no.2, pp.140 - 145 | - |
dc.relation.isPartOf | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.title | MACROMOLECULAR BIOSCIENCE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 140 | - |
dc.citation.endPage | 145 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | BIOMATERIALS | - |
dc.subject.keywordPlus | FORCES | - |
dc.subject.keywordAuthor | FRET | - |
dc.subject.keywordAuthor | ligand | - |
dc.subject.keywordAuthor | receptor | - |
dc.subject.keywordAuthor | rheological measurement | - |
dc.subject.keywordAuthor | specific interaction | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/mabi.200700169 | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.